In order to produce ozone, an oxygen source is needed. One can either use an oxygen concentrator or an oxygen tank. Both have pros and cons. A concentrator offers independence, an oxygen tank offers a higher purity. There are medical oxygen tanks (CGA 870) and industrial oxygen tanks (CGA 540). Both require low flow (pediatric) regulators. Industrial tanks can be filled at welding shops. Medical tanks require a doctor’s prescription.


Each ozone generator used for personal treatment has to be fed by an oxygen source.

There are two basic options: concentrator or tank.

Noise level moderate none
Consumes electricity yes no
Requires refills no yes
Requires filter changes yes no
Requires regular maintenance/testing yes yes
Risk of injury minimal, unless placed too close to a fire source when on tank is under extreme pressure; should not be placed close to a fire source when open; should be out of children’s reach
Cart not needed highly recommended
Nitrogen content negligible, less than 1%   0
Oxygen purity varies, usually 90% +/- 5% 99% and up
Low oxygen flow


needs to be remodeled or used with an external regulator for $150

 pediatric regulator for $70
Cost High upfront cost, low running costs for power consumption Low upfront cost, higher running costs for refills.


Concentrators take in the ambient air which is made out of around 78% nitrogen and 21% oxygen, put it through filters and a compressor and out comes a gas mix of around 95% (+/-) oxygen, some argon, nitrogen and CO2.

Most concentrators produce O2 flows between 0 and 5 liters per minute which are too high for ozone therapy. Ozone applications require extremely low flows between 1/32 to max 1/2 liter per minute. Concentrators with low flows are more difficult to find and often cost more than concentrators with higher flows.

An external low flow regulator can be attached to a high flow oxygen machine, and so “remodeled” into a low flow concentrator.

Concentrators fit for ozone therapy should produce oxygen of at least 90% purity.

Most concentrators use zeolite filters which filter out nitrogen. The remaining 5% to 10% are mostly argon, and some carbon dioxide (CO2). The nitrogen content is negligible to non-existent. 

Protocols like insufflations, ozonating water, ozone saunas, bagging and in general everything that is not invasive can be performed with oxygen concentrators.

Concentrators do not require refills like tanks. With access to electricity, one has a near unlimited and continuous supply of oxygen. Concentrators have filters which should be exchanged regularly.

In order to buy a new oxygen concentrator, most states require a prescription. Refurbished concentrators can be acquired without a prescription.

Oxygen tanks can be either medical (CGA 870) or industrial (CGA 540).

Medical tanks have a different valve from industrial tanks, hence require different regulators. Medical tanks have a chain of custody, no such thing is required for industrial tanks. A lack of chain of custody means, it cannot be excluded that the tank was handled in an inappropriate manner which allowed impurities to enter.

There is a way to maintain a chain of custody with industrial tanks and make them nearly as safe as medical tanks:

“Buy a new oxygen tank, tag it in some manner, and when you get it filled/refilled, demand your personal tank back. You will then establish a chain of custody. The oxygen can be considered medical grade because you started with a clean tank having no contaminants”


Having a filled tank at home comes with some risks: the gas inside the cylinder is under extreme pressure. A mishandling could turn it to a missile and hurt humans and damage property. Consequently, it is of utmost importance to secure an O2 tank by keeping it in a cart, or bolt it to a wall, keep it out of the reach of children and away from heat sources. 

A tank needs to be regularly inspected to make sure the valve is still intact.

It does not consume electricity, does not create noise, but requires regular refills.

To refill a medical tank you will need a prescription from a doctor. To refill an industrial tank, you just need a welding shop or a gas supplier.

Except for the Ozonette, none of the ozone generators presented on this website have been approved for medical purposes. Any application of the machines for other than water purification is at the sole risk of the user.


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Legal Disclaimer

Information provided is for informational purposes only and is not a substitute for professional medical advice. No health claims for these products or diagnostic tools have been evaluated by the United States Food and Drug Administration (FDA), nor has the FDA nor any other medical authority approved these products to diagnose, cure, or prevent disease. Since every person is unique, we highly recommend you to consult with your licensed health care practitioner about the use of ozone products in your particular situation. Neither The Power of Ozone nor the manufacturers of these items are responsible for the misuse of this equipment. It is highly advised to receive professional council from a licensed doctor before using Ozone Therapy or any of the mentioned products or tests on yourself.

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