How to Do Nasal Insufflations with Ozone

by | Apr 9, 2020 | 2 comments

During nasal ozone insufflations a mix of ozone and oxygen is introduced into the sinus area.

For this, a syringe, silicone covers, and a relatively low ozone concentration of 5 to 20 mcg/ml are used. 

Nasal insufflations with ozone can be easily done at home.

Introducing ozone into the sinus cavity can help with congestions, stuffy nose, upper respiratory infections, allergies, brain fog, and other brain related conditions.

Here is what you need and how to them:

Which ozone equipment do you need to do nasal insufflations with ozone?

  • oxygen source (either an oxygen tank or an oxygen concentrator) and regulator
  • ozone generator
  • syringe filling station
  • a syringe
  • syringe covers
  • luer lock connectors
  • silicone tubing

Scroll down to find links to the equipment I used in the pictures below. 

How to do nasal insufflations with ozone: step-by-step


  1. Screw the low flow regulator onto the oxygen tank.

2. Take a piece of tubing and connect one end to the regulator. 

3. Take a luer lock connector and push it into the other end of the silicone tubing. 

4. Screw the end with the luer lock onto the “oxygen in” port of the ozone generator.

5. Screw the syringe filling station onto the “ozone out” port of the ozone generator. 

6. Make sure the OFF knob on the filling station is turned towards the syringe port.

7. Plug the ozone generator into the power supply. 

8. Open the oxygen tank with half a turn on the valve. Watch the gauge jump up on the regulator.  

9. Pick the correct settings on your ozone generator. I chose an ozone concentration of 7 mcg/ml which means that I need to set the oxygen flow to 1/4 LPM and the first ozone output dial to 1. 

10. Set the oxygen flow on the regulator to 1/4 LPM. 

11. Screw the syringe onto the filling station. 

12. Set the first dial of the Promolife Dual Cell to one. The second dial remains in the OFF position. 

13. Turn the OFF knob on the filling station so that it points towards the destructor. Now ozone/oxygen gas is flowing into the syringe. 

14. Fill syringe until the 20 cc mark. 

15. Turn the OFF knob on the filling station towards the syringe. This stops the ozone/oxygen flow. 

16. Turn the ozone generator off. 

17. Turn the regulator to zero. 

18. Unscrew the syringe from the syringe filling station. Keep it upright.

19. Put the silicone cover on the syringe. 

20. Take a deep breath. 

21. Insert the syringe into a nostril. Keep the other nostril closed and inject the content of the syringe into your nose, all the time while holding your breath. 

22. Remove the syringe and keep your nose pinched. Keep holding your breath for another 10 seconds. 

23. Release the ozone from your nose and mouth by exhaling. Make sure to move away. Do not breathe it back in. 

24. Do the same with the other nostril by repeating steps 10 to 23. 

25. When you’re done, close the valve of the tank. Don’t exert too much force. 

26. Release the pressure in the regulator by opening it all the way, here it’s 4 LPM. Wait until the gauge goes down to zero. It will take only a few seconds. Then set the regulator to zero again. 

Recommended equipment

This is the equipment I used in the pictures above:

  • Oxygen source: oxygen tank, (or buy / rent it locally)
  • Low flow or pediatric regulator
  • Ozone generator: Promolife Dual Cell
  • Syringe filling station
  • 60 cc ozone resistant syringe
  • Silicone covers for the syringe
  • luer lock connector
  • 3 ft. silicone tubing (I prefer to use silicone tubing instead of PVC tubing for everything. It makes for a tighter fit. I used a 3 ft (ca. 1 m) piece. You may need more or less, depending how far you want to place your oxygen tank from the ozone generator.)

Legal Disclaimer

Information provided is for informational purposes only and is not a substitute for professional medical advice. No health claims for these products or treatments have been evaluated by the United States Food and Drug Administration (FDA), nor has the FDA nor any other medical authority approved these treatments or products to diagnose, cure, or prevent disease. Neither The Power of Ozone nor the manufacturers of these items are responsible for the misuse of this equipment or the information on this page. It is highly advised to receive professional council from a licensed doctor before using ozone therapy or any of the mentioned products or tests on yourself.

About the author:

PaolaI’m Paola the Crazy Old Ozone Lady behind The Power of Ozone. I’m a licensed naturopathic practitioner, natural health consultant, ozone therapy enthusiast, researcher, and ozone therapy analyst. I hold certificates in ozone therapy, hyperbaric ozone applications, Oxyvenierung, and the Andrew Cutler chelation. I own several ozone generators including a German hyperbaric 10 Pass machine. I have been using ozone for over 13 years, I’ve chelated with the ACC program for close to 5 years and I’ve been carnivore for nearly 1.5 years. This website serves as a resource for those who are interested in ozone therapy and other approaches to successfully manage chronic conditions.

Paola Dziwetzki, NP

I’m Paola, aka the Crazy Old Ozone Lady. I help people use ozone therapy in the most effective way. I have used ozone and diet to successfully treat psoriasis, joint pain, chronic fatigue, a low immune system, herpes infections, and a few other conditions.
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Affiliate Disclosure

This website contains links to vendors of products I endorse, including If you decide to make a purchase through one of my links, they will pay me a commission. This does not influence my opinion about the products, as you can see from my reviews.


  1. Graham

    Love that, even a dummie like me can’t go wrong, just need to get a filling station now.
    How long did you take to get pic 23 just right, looks like you are blowing us all a kiss!!!

    • Paola Dziwetzki

      Hi Graham,

      glad you like it.

      That one didn’t take that long, but had to reshoot #20 forever LOL.



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