Oxalates and Ozone – An Introduction

by | Last updated: Jun 26, 2018 | 30 comments

Around three months ago, I was so sick I thought I would kick the bucket. Check out. Go belly up. 

Things were baaaad. I couldn't think, walk, or drive. I was lying in bed all day. I couldn't function. Within 2 months I had lost 26 pounds. Something was destroying my body and mind and I didn't know what it was and neither did the doctors. 

In the end, it was ozone which played a huge part in my recovery.

This life-changing situation made me stumble upon an issue which I believe plays a big role for many chronically sick patients.

This problem can likely explain why many people respond to ozone the way they do. What many take as an ozone induced die-off or Herxheimer reaction could be actually something completely different.

Most people have never heard of it. Yet it is probably the cause of many degenerative diseases, chronic illnesses, and even ageing. 

What I'm talking about are oxalates.

Oxalates are sharp, crystal-like structures which we all take in through plant food. They can settle anywhere in our bodies: brain, heart, lungs, blood vessels, joints, you name it. Causing a plethora of symptoms.

From diagnosis, to causes, and treatment — this is an extensive subject which I intend to cover more in depth in future articles.

This post is a first introduction into the topic. In upcoming posts, I will also describe my personal ozone protocol which helped me get from death's door to being active every day again.

So stay tuned.

What are oxalates?

Oxalates are crystal-like structures that are contained in all plant based foods. All fruits and vegetables contain them. Some to a lesser, others to a larger degree. They're a type of protection mechanism which plants employ against bugs. Unlike animals, vegetables can't run away from their predators, so they use oxalates as a type of chemical weapon.

Just as toxic as oxalates can be to worms and insects, they can also do damage to humans.

Calcium oxalate crystals in a urine sample. The sharp edges can damage tissue inside organs and cause chronic inflammation. 

What do medical doctors say about oxalates?

According to conventional medicine, oxalates mostly affect kidneys. Around 80% of kidney stones are made of calcium oxalate. Patients with kidney disease are prone to develop oxalate deposits in bones, joints, heart, eyes and skin. 

Oxalates have been also found in blood vessels and thyroid tissue in patients with no known history of kidney impairment.

One study has found up to 3-fold oxalate levels in urine samples of autistic kids without any sign of kidney damage.

Acute oxalate poisoning happens after ingestion of anti-freeze (ethylene glycol) which converts to oxalates. The resulting kidney and brain damage can be lethal.

Some people also have a genetic predisposition which results in the internal production of oxalates. It is called primary hyperoxaluria and is also characterized by kidney damage and deposits in bones and blood vessels.

Once in the blood stream, oxalates bind to minerals like calcium, magnesium, zinc, potassium or phosphorus, leaving deposits in various organs and other tissue.

Too many oxalate crystals in the blood can lead to both calcification or brittle bones. Both are observed in people with genetic hyperoxaluria. Bones become weak because of the mineral loss. At the same time calcification in other parts of the body can take place due to the deposited calcium oxalates.

Once oxalates are stored in the human brain, a whole variety of psychological, cognitive, emotional symptoms emerge. Fine motor skills can become impaired as well.

In this and the following article I will be mainly focusing on secondary hyperoxaluria, which means the occurrence of increased oxalate levels through food intake.

Who develops oxalate issues?

Susan Owens, an independent researcher who has been looking into oxalates for nearly two decades, says there is no such thing as an “oxalate sensitivity”. According to her, we all absorb oxalates through food and deposit them in various organs. The best term to describe this phenomenon is “oxalosis” and it happens to every human being. Some people deposit oxalates to a very small degree which does not lead to any immediate problems. Others absorb the crystals to a much larger degree. The resulting build-up can lead to a whole range of neurological and physical symptoms. 

Nuts are among those foods which contain a lot of oxalates. People on a vegan or a paleo diet who consume a lot of nuts are at risk to develop a high oxalate burden. The Facebook group “Trying Low Oxalates” has a good list with high and low oxalate foods. 

Reasons for oxalate build-up

Increased absorption of oxalates can happen because of:

Fat malabsorption

Most oxalates which we ingest through food are bound to dietary calcium and are excreted through stool. They leave without creating further problems. Unless there is fat malabsorption. In this case the fat binds to the calcium instead of to the oxalates. There is no remaining calcium to take care of the oxalates and the crystals can end up in the blood stream from where they are transported to various organs.

Leaky gut

Inflammation in the digestive tract can thin the colon lining and destroy the protective mucus. This allows oxalate crystals to pass through the gut wall into the blood stream. Inflammation can stem from food sensitivities, infections, or a lack of stomach acid.

Endogenous production

In some cases, when there is a lack of Vitamin B6, B1 or zinc, the body can produce oxalates in the liver. One of the ways to study oxalate problems in lab rats is to induce Vitamin B6 deficient. Apparently, this condition can be reversed relatively easily by the appropriate supplementation.

Impaired microbiome

In a healthy human with an intact biome, there are a number of good bacteria which degrade most of the oxalates — so they don't pose an immediate problem. The majority of oxalates in a person with healthy levels of colon bacteria are excreted through the stool.

The most essential bacteria to digest oxalates is oxalobacter formigenes. This species may reduce the formation of calcium oxalate kidney stones. 

In a person with a compromised microbiome oxalates absorption can be as high as 50%.

Why does a microbiome become impaired? 

There are several likely culprits:

• Antibiotics

Anyone who has ever taken antibiotics is at a risk of having impaired gut bacteria. The most important oxalate-degrading bacteria, oxalobacter formigenes, is very susceptible to a variety of common antibiotics. This type of good bacteria isn’t available as a supplement: You can't buy oxalobacter formigenes as a probiotic. So once it's gone, it's gone for good — unless it is re-introduced into your biome through specific procedures like a fecal matter transplant from a healthy donor.   

Other oxalate degrading bacteria include bifidobacteria and lactobacillus which can probably make up for a lack of o. formigenes, at least to some degree. Unfortunately, if you have already a high oxalate burden, this can prevent lactobacillus bacteria to settle in, since too many oxalates can also kill lactobacillus bacteria. This can turn into a vicious cycle. 

The link between an impaired bacterial population in the colon and oxalate buildup is evident in the fact that the use of antibiotics increases the risk of kidney stones.

• Antibiotics in meat

There's reason to believe that the antibiotics from meat we eat can negatively impact the bacterial composition of our colon. This article explains the connection between too many antibiotics being absorbed from the consumption of meat from livestock which has been treated with antibiotics and an imbalance among your gut microbiota. Another reason to use organic meats only. 

• Mercury toxicity 

Anyone who ever had amalgam fillings is at risk of having a disturbed gut biome. Mercury — like every other toxic metal — is very good at killing all sorts of bacteria, including gut bacteria. Even after the amalgam fillings have been removed, the mercury is still there. And not only has it killed off the good bugs, but the mercury remaining in the system can make it difficult for the colon to be repopulated again. Mercury can also cause leaky gut, a thinning of the intestinal walls, a problem which may also exacerbate oxalate issues.

• Food poisoning

Incidents of food poisoning can decimate a healthy gut biome, lead to a whole range of food sensitivities, and allow oxalates to be absorbed into the blood stream.

Up to two liters of ozonated water — this has been my breakfast nearly every day of the past three months and counting. 


Ozone and oxalates – an uncharted territory

How does ozone get into the picture? Does it help the body get rid of them?

Three months ago when I was so sick that I couldn’t work on my computer, drive, or even walk, ozone was what turned me around.

So yes, I have reason to believe that ozone can play a huge role in clearing oxalates.

How it does that, is as of yet pure speculation. As far as I know, there is no research about oxalates and ozone therapy. A google search doesn’t turn up any information.

The biggest group when it comes to dealing with oxalates is the Trying Low Oxalates group on Facebook. It has nearly 15,000 members and has been founded by the above mentioned oxalate expert Susan Owens. But even there one can not find a single entry on the topic, apart from mine. It appears that I am the only one so far who has connected those two areas.

So everything I write about how ozone could possibly help clear out oxalates is pure speculation.

Inspite of a lack of research, there is no doubt in my mind that ozone helps with oxalates. 

Why I think that and which ozone induced symptoms are a probable sign of oxalates leaving, this will be the topic of another article.

Stay tuned.


About the author:

PaolaI’m Paola the Crazy Old Ozone Lady behind The Power of Ozone. I’m a licensed naturopathic practitioner, natural health consultant, ozone therapy enthusiast, researcher, and ozone therapy analyst. I hold certificates in ozone therapy, hyperbaric ozone applications, Oxyvenierung, and the Andrew Cutler chelation. I own several ozone generators including a German hyperbaric 10 Pass machine. I have been using ozone for over 13 years, I’ve chelated with the ACC program for close to 5 years and I’ve been carnivore for nearly 1.5 years. This website serves as a resource for those who are interested in ozone therapy and other approaches to successfully manage chronic conditions. 

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  1. mike kopplin

    Hi! You're right on with your ozone oxalate connection. I've been using ozonated water to get rid of kidney stones for over 20 years. Whenever I have a stone moving through my system, a day of drinking ozone water will completely destroy it and get me back to normal. The stones are made of oxalate and they only go away with ozonated water. It was a miracle that a natural healer introduced to me in 2003. I'm sure it would be a more popular “cure” if it wasn't free and easy.

    • Paola Dziwetzki

      Hi Mike,

      Thank you for sharing. Yes, I also believe that ozone can help in that regard.

      Chanca Piedra is another great remedy.

      Potassium chloride and magnesium chloride (orally or topically) seem to help as well.


  2. Vanessa

    Hi Paola!

    First things first, I am loving your work, thanks a trillion for your research and all you share. Very valuable!

    I am a newcomer to ozone, and learning very fast because I am in great need (have the exact symptoms you describe on this post plus some others… I am putting the puzzle pieces of culprits together: glutathione supps, mercury, viruses, diet… phew!!)

    After reading your post, I would love to know your opinion on this other version of oxalates and what really goes on around that issue, from a very different dietary perspective to the ones you share:

    Would this make sense to you?

    It is a privilege to be able learn from each other in this way. Thanks again for your work!

  3. Sharon

    I know that oxalates can be made from excess Vit C. I’m Ozoning as I’m oxalates dumping on carnivore for 6 months now. Do you think juicing two lemons per day is enough Vit C while I’m ozoning almost daily?
    I also take citric acid with all the minerals in citrate form. Again, thank you so much for all your help! I adore your videos. You take no prisoners! Love it!

    • Paola Dziwetzki

      Hi Sharon,

      thank you for watching my stuff 🙂

      How much ozone do you use per day? If you're carnivore, I would check your vitamin C levels, do a blood test.

      2 lemons may be enough, but depends how much ozone you use …


  4. Sharon

    Thanks so much!
    I think I’ll use a lemon or lime fresh squeezed in water first thing in the morning to replenish Vit C levels going forward! Thanks for the info!
    I had no idea that ozone depletion of Vit c!
    Thanks again!

    • Paola Dziwetzki

      You're welcome.

      But am not sure a lime would be enough …

      If you're doing a lot of ozone regularly, then getting your Vit C levels tested may be a good idea also …

  5. Sharon

    Hello, I watch you avidly! You’ve taught me how to do everything with ozone! Thank you so much!
    I just started carnivore diet 19 days ago coming from keto with HIGH oxalates and dumping so much… which best way to ozone for oxalate dumping…neurological systems-tingling skin like shards glass. Had to take antihistamines. I have ozone sauna too. Is this best? Thanks so much! You’re the BEST!

    • Paola Dziwetzki

      Hi Sharon,

      love to hear that you got some helpful information out of me.

      The idea that ozone could help with oxalate dumping is a speculation of mine (but oxalate expert per excellence Sally K. Norton seems to have the same idea) which has never been researched. So, my recommendations are just guesses: I would see if drinking ozonated water helps, and yes, ozone saunas, too.

      Let me now how you'll do.


    • Sharon

      Oh Paula, I thank you so much! I’m also using the citrates- calcium, magnesium, potassium and zinc to chelate the oxalates as well. I’m doing o3 water, sauna and vaginal ozone and kicked all veggies out of my diet. I will be carnivore forever from now on! I pray I can heal snd be well again!
      I do appreciate all your videos. You cannot imagine the wonderful resource they’ve been to me on my healing journey! God bless you in this nee year 2021!

    • Paola Dziwetzki

      Hi Sharon,

      thank you for the kind words.
      But a tip if you're planning on going carnivore AND doing ozone: I recommend to supplement with Vitamin C in such a case, since ozone can degrade our Vitamin C stores …
      Calcium ascorbate is a good easy to digest form, or if you want to get it from food sources, then lemon or lime juice is a good option, or sauerkraut juice.


  6. R

    You are doing some good honest work.

    I think it is possible that ozone can help oxalate issues based on my own health where I have SNPs related to that. I have yet to completely work out as to the reason why, biochemically, it works. There are so many factors to consider even outside the chemistry too.

    I would be interested in additional findings you get.

    Thank you for your work

    • paola d

      Hi R,
      thank you!
      I would also suggest to follow Sally K Norton. She has lots of information about oxalates.

  7. Vital

    Sorry, I forgot one more thing: Do you know if something can be done in the case of fat malabsorbtion, so the fat doesn't bind to the calcium?



  8. Vital

    Hello Paola,

    It's good to read that ozone helped you so you are doing much better now.
    But how did you find out that oxalates were the cause?
    Could you detect that the body excreted a lot of oxalates after the ozone therapies?

    Another thing, I wonder what are the upper limits for beneficial ozone applications.
    Most recommendations say not to apply it every day, and only in small amounts.
    I believe the gentleman in your interview, who treated his Lyme disease, said he applied it rectally for half an hour at a time, obviously without any ill effects.
    Do you see a reason why one should not do a rectal-, a nasal- and an ear insufflation on the same day and every day?

    Many thanks in advance!


    • paola d

      Hi Vital,
      I offer 30 min sessions for people who have questions: https://thepowerofozone.com///bookme/
      This may be an option for you to get answers.

  9. Wayne


    Dealing with stage 3, 4, and 4 & 5 prostate cancer that has moved to bladder, bones, etc. Ozone appears to be aiding in killing cancer and more.
    Had 6 or 7 bowel movements, yesterday partly because of the Ozone. Great seeing my colon start working.

    Looking for higher levels (highest possible) of Ozone for myself. Deathbed cancer and it appears Ozone to be aiding in destroying my cancer and whatever else I have been needing.

    Noticed Dr. Liebowitz was using 10-packs into blood get to a good working Ozone value. This clue tells me the more Ozone the better.
    Money for his treatments is always a cost factor with me being so poor.

    Doing Bladder, Rectum, and drinking Ozonated liquids.

    – Looking for ways to Ozonate my blood through the skin.

    Using needles would be an option if I could find the supplies for treatment at home.
    – Also looking for other ways to get Ozone into my blood.
    Thinking about Ozoning DMSO and distilled water and spraying all over my body.

    Note: The body moves all of its blood in the body in 3-minutes.

    There should be a way to put Ozone on the skin and continue feeding Ozone to that area of veins for absorption into the blood.

    Anyone got any clues, please contact me at support @ StopCancer.com

    Medical Level
    Hopefully, this is a good Ozone unit? Any ideas?


    • paola d

      Hi Wayne,

      you may want to look into ozone saunas if you want to get ozone through the skin: https://thepowerofozone.com///protocols/ozone-sauna/

      That unit could work, although I do not recommend buying from China. “Cheap is expensive” as my German plumber used to say.

      I would also look into drinking ozonated water, rectal insufflations (to get the ozone as close as possible to the cancer), and the carnivore diet: meatheals.com .


  10. Tom Campbell

    Hi Paola
    Do you sell the complete unit with the ozone mach & body bag & whatever
    else is need to get started

    approx total cost


    • paola d

      Hi Tom,

      I do not sell anything, apart from consultations …


  11. Laura

    I too, really appreciate your article Paola, thanks for sharing this info

    Glad to hear that you are feeling better after solving your Oxalates problem.

    • paola d

      Hi Laura,

      thank you for reading and commenting!


    • laura

      Hi Paola,

      Just wanted to let you know the good news after trying everything for years to try and clear my acne/red spots on my face which would bleed and not heal… after just 2 weeks of a low oxalate diet and potassium magnesium citrate, they have finally started to subside and my face has not looked this clear in years.

      God Bless

    • paola d

      Hi Laura,
      that's great news! Thank you for sharing!

  12. Christina

    Stay healthy and strong and big thank you for your time and info sharing . Bless you

    • paola d

      Thank you, dear!

  13. Shaun Talbot

    About you:

    “Hi! I’m Paola, the Crazy Ozone Lady and self-proclaimed ozone junkie. I've been using ozone on and off for 12 years and still discovering new things every day.”

    And your quote:

    “Around three months ago, I was so sick I thought I would kick the bucket. Check out. Go belly up.

    Things were baaaad. I couldn’t think, walk, or drive. I was lying in bed all day. I couldn’t function. Within 2 months I had lost 26 pounds. Something was destroying my body and mind and I didn’t know what it was and neither did the doctors.”


    I find it very suspicious that you use Ozone, and you got extremely sick. This is not normal. Perhaps you might want to rethink your world view?

    • paola d

      Hi Shaun,

      I suggest you rethink your way of doing research and how you draw conclusions before you post smartassy comments again.

      One of the reasons why I am able to answer you at all is because I restarted using ozone every day around 5 months ago.

      The 4 years before that I was doing ozone only sparingly. Sometimes not using my ozone equipment for up to half a year or longer since I was concentrating on chelation during that time. And that was likely one of the mistakes. Had I been doing more ozone more consistently, my health would have probably never precipitated the way it did 5 months ago.


    • Dr. Keith Kantor

      Hello Paola,
      Interesting article.
      Thank You
      Have you heard of oxalate neutralization with hydroxide water?
      Seems to be helping folks with high levels.
      Please follow link to web-site I gave.
      Dr. Keith Kantor

    • paola d

      Hi Dr. Keith,

      no I haven't.
      There may be something to it. May be the same reason why I theorize that ozone helps with oxalates as well.



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