by | Dec 12, 2018 | 95 comments

PLEASE READ FIRSTHow to protect yourself from breathing ozone
What are vaginal insufflations?
What equipment do you need?
How to perform vaginal insufflations
Risks and how to avoid them


You perform vaginal insufflations by infusing an ozone/oxygen gas mix into the female reproductive system with the help of a catheter. They are best performed in a continuous fashion: one attaches a catheter to the ozone output hose and allows for the ozone/oxygen gas mix to flow in for the desired amount of time.



Here is what you need in order to perform VI directly from the ozone generator in a continuous fashion. Which in my opinion is the best way to do it.

You need:

1. Oxygen source (tank or concentrator) including low flow regulator

2. Ozone generator

3. Extra silicone tubing, connector, catheter

[3a.  OPTIONAL: humidifier and trap]

4. Mask

5. Extras: at least two old or white towels, some plastic cover, a good book


In the picture above you see the most basic setup for vaginal insufflations: an oxygen tank (although I prefer using an oxygen concentrator and an external low flow regulator), the Promolife Dual Cell O3Elite, some extra silicone tubing, a special connector and a catheter

1. Oxygen source:

Either an oxygen tank or an oxygen concentrator can be used which produces oxygen of at least 90% purity. Whatever oxygen source you choose, make sure your ozone generator is able to produce concentrations between 20 and 50 mcg/ml at the given oxygen flow. Consult the chart of your ozone generator to find out whether you will be able to produce those concentrations.

2. Ozone generator: 

It should be an oxygen fed generator which can produce ozone concentrations of at least up to 50 mcg/ml. Any of the recommended generators on this page will do the job. The one in the pictures above is the EliteO3 Dual Cell from Promolife.

Get a longer piece of silicone tubing to comfortably sit or lie during the treatment. 

This connector is a catheter adapter. It fits the standard or silicone catheters

You can use either the standard or silicone catheters. You can also use luer lock catheters and a luer lock connectors to attach it to the silicone tubing. 

3. Silicone tubing, connector, catheter: 

Take 3 to 4 feet of silicone tubing, use a luer lock on one side (to connect it with the ozone generator) and this adapter on the other side. The adapter fits perfectly into the catheter. Use either standard catheters with the orange top or silicone catheters. They can be reused. Just rinse them with warm water. 

In the picture above you see the setup for vaginal insufflations with trap and humidifier. The trap protects the generator from water. It humidifies the ozone. 

[3a. OPTIONAL Trap and humidifier:

with prolonged insufflations increased dryness can occur. Running the ozone through water first can mitigate or prevent that. The trap serves to protect the ozone generator from water which tends to travel back through the tubing. Insert enough water into the humidifier to cover the stem, so around 1/3 to 1/2 full. The trap must remain empty and is placed between the ozone generator and the humidifier. So the ozone travels first into the trap, then into the humidifier with water, then into the silicone tubing and then through the catheter.]

One of the best ways to protect yourself from breathing the escaping ozone: a mask with either a #2097 or #2128 filter. 

Make sure to protect your furniture. Especially if it’s an awesome pink velvet couch ;-). 

Put some extra towels on top of the plastic and on your crotch. 

4. Mask:

During VI a lot of ozone can escape into the room. You want to protect yourself from breathing it in as much as possible. What I have found works the best is wearing a mask which filters out ozone. An additional fan and good ventilation through open windows offers extra protection. 

5. Extras: Towels, plastic cover, a good book

Use the plastic to cover your furniture. Ozone bleaches every fabric it comes in contact with. Just keep in mind that over time, the plastic will be destroyed by ozone. So either regularly check that the plastic is still intact, or get a piece of silicone sheets, or treat it with a silicone spray. Put one towel on top of the plastic and the other one on top of your crotch. It will absorb some of the ozone. During the VI you can relax and read or work on your computer.

I don’t even know what is better: the book or the movie? I’ve watched some scenes of the movie 10 times when it was available on Netflix. It’s just absolutely brilliant. Whether you read or watch movies on your computer: just lean back and enjoy the bubbles! 


1. Prepare everything: put the plastic and the towels on your couch, connect the oxygen source with the ozone generator, plug both into the power supply (if needed), connect the silicone tubing and the connector to the ozone generator. 

2. Open or turn on the oxygen source. If it’s a tank: open the valve of the tank and the regulator at a low flow of 1/8 LPM. If it’s an oxygen concentrator: let the machine warm up for a few minutes, then adjust the external regulator to 1/8 LPM. 

3. Put the mask on. 

4. Undress, sit down on the couch, and insert the catheter.

5. Connect the catheter with the silicone tubing. 

6. Set the ozone generator to the desired ozone concentrations. 20 to 50 mcg/ml is sufficient. 

7. Read a book or work on your laptop. Start with 10 minutes three times a week. Work up slowly to 20 to 30 min daily. 

8. After you’re done turn off the ozone generator, turn off or close the oxygen, remove the catheter, and rinse it out with warm water. You may reuse it.





  • Some burning, or itching
  • Transient sensation of warmth
  • Bloating
  • Pain or cramps
  • Rash
  • Redness, feeling sore
  • Reduce the ozone concentration, frequency, or duration of applications. 


  • Open wound in the reproductive system
  • Transplanted organ
  • Hyperthyroidism

Legal Disclaimer

Information provided is for informational purposes only and is not a substitute for professional medical advice. If you're sick, please consult a medical professional, not a Crazy Ozone Lady on the internet. Don't take anything I'm saying as a promise to cure or diagnose anything. The machines presented are primarily water purification devices. If you're using them for anything else, you're doing so on your own risk. I do not carry responsibility for what you decide to do with the devices. Neither I nor the manufacturers of these items are responsible for the misuse of this equipment. It is highly advised to receive professional council from a licensed doctor before using ozone therapy or any of the mentioned products or tests on yourself.


Affiliate Disclosure

This website contains affiliate links, which means I may receive a percentage of any product or service you purchase using the links in the articles or advertisements. You will pay the same price for all products and services, and your purchase helps support me and my craziness.

Thank You for your support!


  1. karina

    What’s the ideal position for administering VI? Sitting? Laying down?

    • paola d

      I prefer to sit and work on my computer while insufflating. Find the position most comfortable for you.

  2. Jane Laursen

    IS the catheter used the same as for RI’s?

    • paola d


  3. Lia

    for systemic ozone is there any information re: rectal vs vaginal insufflation? The info I can find on rectal is that is is 80-90% as effective as MAH. I have successfully completed surgery ( 1 positive lymph node)chemo and radiation for aggressive uterine CA and now want to increase immune system and weaken any possible remaining cancer cells.

    • paola d

      Hi Lia,
      there is conflicting information on rectal and vaginal insufflation.
      Some allege that RI are a systemic treatment, others doubt it.
      The Cubans are big on rectal insufflations and seem to successfully treat a whole range of conditions with it.
      Vaginal insufflations are poo-pood by some, and embraced by other ozone experts.
      From personal experience I know VI are a systemic treatment, most likely through the lymphatic system.
      If I had had treatments for uterine CA, I would most likely concentrate on VI and some form of systemic treatment like ozone IVs at a doctor’s or ozone saunas.

    • Lia

      Thank you Paola — just found this site again. Started VI and RI at home and have 2 10 pass scheduled starting the first of January. Then plan on doing a series of MAH. Also do some EI for about 2-4 minutes 3-4 times a week.

      Thanks again

  4. Diane

    Is it okay to put ozone up the vagina everyday?

    • paola d


    • Christie

      Hi Diane,
      I’m not sure I would recommend VI everyday, from what I have seen in many patients, it can dry out the tissues and cause bleeding. Give the tissues a break atleast a couple days a week, and if bleeding occurs, I would stop for a few days and proceed with a reduction in frequency.
      Lets remember that VI is also effecting your body’s natural vaginal normal flora. We dont want to kill off everything down there and there is little research as to the effect of VI on your healthy bacteria.
      Personally, I would only receive this treatment multiple times a week if I was treating a vaginal infection or disease process, such as cervical cancer.

    • paola d

      I don’t think I’ve ever heard someone report bleeding after VI. There may be some blood spots if the walls in the vagina were indeed too dry and some tissue got attached to the catheter.
      But this is not something to be really concerned about.
      If there is increased dryness one can also use a humidifier.
      I have found that VI actually stimulate vaginal secretions.
      Also the vaginal flora is a) not as important as intestinal flora. You don’t need the vagina for survival, and b) because of how shallow and how easily accessible it is (relative to the intestines), it’s really easy to repopulate it. I’ve had my flora tested after months of doing VIs for sometimes up to 60 min and everything was perfectly fine, the doctor said. This was after around a 1 month brake from VIs.


  5. Shannon

    I had VI ozone today for the first time by a naturopath. I have neuro lyme. He used 3 syringes of ozone via a catheter.
    I was lying down for the procedure. When I sat up there was copious fluid on the bed. The doctor didn’t know what that it was. It was clear and had no odour. It definitely wasn’t urine. What was this fluid that drained out of me and why did it happen?

    • paola d

      I don’t know exactly what it was.
      VI can stimulate natural secretions, maybe that is what it was?

  6. Kimberly

    I have actually found a vaginal insufflation device designed specifically for this use. It’s a vet supply, but I found out that the unit was actually designed for human use. This way you don’t get excess ozone escaping into the room and potentially damaging your lungs

    • Johanne

      Thank you Kimberly.
      I also bought it on o3vets for VI but promolife sells it for a lower price.
      I use the apparatus every other day and reduced a uterine fibroid I started at 20gamma increased every 3 days 20 minutes for each sessions and now I’m at a higher concentration of 53.
      A lot of yeast would come out after each VI
      This apparatus is a great investment since you get continuous flow.

    • Doina

      Hi Kimberley, which is the product from this page that you are referring to? Interested in buying something different for VIs than a catheter!

  7. Elizabeth

    I started vaginal ozone yesterday and immediately felt clear headed and more energized. Today I am experiencing a lot of yellow discharge. No odor and no pain/itch etc. I feel fine but the discharge is alarming. Anyone else have this happen?

    • paola d

      Hi Elizabeth,
      the discharge happens often. It is possible it is just normal vaginal secretions which ozone is known to stimulate.

    • Johanne

      Dear Elizabeth,
      I also had lots of discharge.
      My naturopath told me the discharge is yeast coming out of my vagina.
      I’ve been doing VI now for 3 months every other day for 20 minutes per session with continuous flow. As I increased the dose more discharge would come out. the discharge is almost non existent now.

  8. Susana


    Did VI ever cause you start your menstruation? I know that I am not suppose to use ozone few days prior and after my menstruation so I normally wait 4-5 days after I’m done. Within two days of doing VI I start my period again and this makes it frustrating! just wanted to get your impute on this.

    • paola d

      Hi Susana,
      no, this never happened to me. But I have heard this a few times. So it seems it is possible.

    • lucy

      hi paola, thanks so much for your incredible info and selfless care. i just recovered from bv which i never get tho i deal with yeast and ph issues regularly. borucki scud suppositories are one thing that really helps. my vagina was in a better more clear place the last couple weeks. i tried vaginal ozone yesterday first time. today i am more off down there than i’ve been with discharge, seems like yeast. from the comments here it seems this is normal detox?

      if so how often do you suggest doing this and how long do these unfavorable symptoms last? i fear doing this regularly if yeast keeps coming up if treatment is long term :/.

      last can i use boric acid suppositories before or after vag ozone? if so do i need to wait a day or anything?

      thanks infinitely

    • paola d

      Hi Lucy,

      it may be the stimulation of normal vaginal secretions.
      In my opinion ozone can also increase an oxalate dump. Reduce oxalates in your diet and see if that helps.
      I have no experience with boric acid, sorry.


  9. Kay

    Hi Paola, I had read that when doing longer VI treatments (2 hours), that the humidification bottle may be attached in order to add moisture & not dry out the vaginal tissue. You’ve been so helpful on everything ozone. Just wondering if you think it’s a good idea or not to add humidification to the VI treatment. Thank you.

    • paola d

      Hi Kay,
      yes with prolonged VI humidification might be a good idea.
      Just make sure you protect your ozone generator from water backflow.


  10. Natasha

    Hello Paola, I am wondering if VI can be as effective in delivering O3 to the blood stream as RI. I’ve been developing painful gas reactions to RI while VI run very smoothly for me, so I prefer to continue with them. It would seem to me as common sense, O3 would penetrate as well from rectal tissues as through vaginal walls? I’ve got a variety of viral conditions am currently treating with it. Thank you!

    • paola d

      Hi Natasha,
      contrary to what most ozone practitioners say, I do not think that RI are a good method to deliver ozone into the blood stream or that they are a good systemic treatment at all. With prolonged treatment one can achieve systemic effects in some conditions, but overall RI are not comparable to intravenous administrations, in my opinion.

      VI are in my opinion a better way to achieve systemic effects if done long enough and with high enough volumes. They are also easier to perform and less messy.

      Yes, I believe that with prolonged application, the O3 and its by-products is able to penetrate the intestinal walls and probably also the lymph.

    • Sing Young Min

      “contrary to what most ozone practitioners say, I do not think that RI are a good method to deliver ozone into the blood stream or that they are a good systemic treatment at all. With prolonged treatment one can achieve systemic effects in some conditions, but overall RI are not comparable to intravenous administrations, in my opinion.”

      *** This is perhaps the most irresponsible comment that I’ve seen on ozone therapy.
      You should provide scientific or clinic evidence for this “opinion”.
      It is obvious to even the most casual observer that O3 is very swiftly and powerfully absorbed by ANY mucous membrane. As evidence I would refer you to your own warning about breathing O3; for anyone who has experienced this, it is clear that ozone gas is IMMEDIATELY absorbed. For some reason the mucous membrane in your colon is unable to absorb while the purity of the vagina can is absurd on it’s face. We may not be in the girl’s club here, but this post of yours is capable of discouraging men from a powerful alternative approach to healing. Post some evidence or perhaps retract your ill-advised train of thought.

    • paola d

      Hi Sing,

      I suggest that you calm down first and stop acting hysterically.

      Once you have achieved that, please provide the following:
      1. Please quote the part where I use the term “purity of the vagina” or where I say that an alleged “purity of the vagina” is what makes that orifice absorb ozone well.
      2. Please quote the part where I say that the colon is not able to absorb ozone at all which is what you’re implying that I’m saying with your overwrought and misleading comment.

      After you have switched your brain back on and reread my page and possibly also watch this video I made on the topic, I suggest you realize that I – unlike people who like to get hysterical online – tend to think in nuances and not in black or white thinking and FOR SURE do not want to discourage 50% of the population to do ozone. What I do want to discourage is people misrepresenting and misquoting what I’m saying.

      Also not sure what you mean with “girls club”. For a club to exist it takes more than one person as far as I know.


  11. Liza

    Hi Paola,

    I’ve been doing regular RI and VI at home, and was wondering what is the ideal gamma and flow setting and length of time to do VI and reach say 5000gamma as you would with DIV? Or is this not possible?

    • paola d

      Hi Liza,

      I think you are confusing concentration with dosage.
      Ozone therapy is commonly applied at concentrations between 20 and 70 mcg/ml.
      The dosage during a DIV of for example 60 ml at a concentration of 30 mcg/ml would be 30 mcg/ml x 60 ml = 1800 mcg.

      In order to reach 5000 mcg at a volume of 60 ml, the concentration would have to be 5000 mcg/60 ml 0r 83 mcg/ml which is way too high. It is above what is considered safe for ozone therapy.

      For VI and RI one uses concentrations of 20 to 50 mcg/ml.

      Depending on the volume and duration of the application one can reach total dosages of several thousand mcg this way.


  12. Jami Piehler

    I own an ozone machine and love using it! I am 37 wks pregnant and just got my Group B Strep test back and it was positive. They want me to do IV antibiotics for all of labor and delivery and I am not comfortable with that. I am wanting to do vaginal ozone to try and eliminate the GBS before I go into labor (anytime now) but cannot verify that vaginal ozone is safe during pregnancy. Do you have any insight on this or can you point me anywhere?

    • paola d

      Hi Jami,
      it is not recommended to do ozone during pregnancies.
      Certainly not beyond the first 3 months.

  13. Nicole

    Hello. I have a few questions. First is, what are your thoughts on performing RI and VI in the same day? And also, what are your thoughts on taking Vitamin C on the days you do either of these? I generally take high doses. Thanks.

    • paola d

      Hi Nicole,

      performing RI and VI on the same day is not a problem.

      If you take Vitamin C, I would space it apart from ozone by several hours, to allow the ozone action to fully enfold.


  14. Karrah

    Hi I was wondering if one can do VI while on period?
    Thank you

    • paola d

      Yes, that is fine.

    • AD.

      “Women must not use this method close to, or during the time of menstruation as ozone at these concentrations increases blood flow.”


    • paola d

      Hi AD,

      I do not agree with this recommendations.
      It depends on the person.
      I’ve done VI during my periods without any problems and without triggering increased blood flow.


  15. Doris Tillman

    I am considering doing VI ozone as a replacement for the expensive IV treatments (200 each). I am using it for the Herpes virus (never had an outbreak, but labs show high antibodies).
    Would you expect VI to be as effective or recommend staying with the IV therapy

    • paola d

      Hi Doris,

      I would not go according to lab results to gauge efficiency of a treatment.
      If you never had an outbreak, then high antibodies could also signify a past infection.
      It is difficult to say without having the whole picture.

      In general I would say that IVs have a different impact than VI.


  16. Jane Haveman

    Can we simply connect our catheter to the tubing coming out of the ozone generator, which has 02 coming into it at 1/8, and then inserting the catheter rectally or vaginally? How long would we keep it in? This eliminates the need for the adapter kit bag.
    Thank you.

    • paola d

      Hi Jane,
      yes, vaginally you can do that.

      If you do it rectally you need to be careful and look at a timer to not exceed 500ml. So at 1/8 LPM this would be 4 minutes.


  17. paola d

    Hi Nancy,

    can I write you an email?


  18. shravani

    I’m 8 dpo and suspecting pregnancy. I was taking vaginal ozone twice a week as per my physician’s advise. Is it safe to continue it?

    • paola d

      Hi Shravani,

      ozone associations do not recommend doing ozone during pregnancy.


  19. Amy

    Hi Paola,

    I was wondering if you know anything about or have any article links where they used Ozone therapy for Endometriosis, PCOS and Uterine polyps (fibroids).

    What therapy and dosage do you recommend for these types of problems?

    Thank you!

    • paola d

      Hi Amy,

      I don’t have any such articles at hand, sorry.
      Doesn’t mean that they don’t exist, but I just don’t know of them off the top of my head.

      I would recommend vaginal insufflations. One can start at 10 min per day and increase to 2 x 30 min.


  20. Jenny

    I went to NY and stayed doing IV ozone for 1 month for my MS, 2-3X per day, 6 days per week. I am now doing VI at home. I have so many questions!
    Does VI break down the vaginal tissue after a while? I am currently doing it 1 HR per day
    Is VI going to be strong enough to replace IV?

    • paola d

      Hi Jenny,
      if you are doing VI at a safe concentration in the 40 to 60 mcg/ml range, then no, there should be no tissue breakdown. Even at 70 to 80 mcg/ml it should be ok, but I would not go higher than that.
      “Is VI going to be strong enough to replace IV?” – I don’t know. Best go according to your response to the insufflations. If you feel they give you benefit, then keep going. Just make sure you stay protected from breathing ozone:


  21. Sue

    Should you avoid sex on the days you do VI?
    Also any suggestions on why RI causes me so much gas pain, abdominal cramping, & bloating? I am doing them directly as directed by my doctor.
    Thank you!

    • paola d

      Hi Sue,
      no, you don’t have to avoid sex on the days you do VI.
      I don’t know why the pain, bloating, and cramping occur. I assume it is because of the gas which is produced when ozone reacts with left-over feces in the colon.
      I also get the cramps and bloating. Which is one of the reasons I don’t like doing RI.


  22. Susan

    I am confused on how much to do for a VI per day? I have cervical cancer and want to do as much as I can, but still be safe. Also how much per day for RI?

    • paola d

      Hi Susan,

      I can’t tell you what you should do for your cancer.

      But I do up to 60 min of VI per day. Others who this experience some serious itching though.

      As to RI: have you watched my video on the topic?


  23. Kay

    Paolo,you are simply awesome thank you for knowledge you’re sharing here. Im pretty new to this,just got the ozone machine i have done VI a couple of times i feel the air escaping ,i connect a catheter to the bag …do i need a different equipment or i don’t insert the catheter in emough?
    And what a the recommendations for an VI.

    • paola d

      Hi Kay,

      the gas *should* escape during VI. VI works differently than RI. RI is an insertion of gas. VI is more a douche or rinsing with the gas.


  24. Betty

    I just started home VI therapy after spending $3000 on MAH ozone at my doctors office. I’m using the “measured” approach where I fill a syringe with a specific concentration (38-52 ug/ml) and use between 150-200 ml of the ozone gas. First off, the extreme energy increase and positive mood obtained through VI seems every bit as intense as the MAH delivery…at least for me.

    Unfortunately I seemed to get a large die off of good bacteria because I had all the symptoms similar to taking antibiotics. I recover after a few day using up to 150B probiotic/day. Could this reaction be due to too high of a concentration or three treatments within a week? The doctor had me take a 50B probiotic/day but didn’t mention that it was for the ozone therapy. The MAH therapy I received was 10-14 days apart over 6 weeks.

    • paola d

      Hi Betty,
      it is unlikely that the amounts, the method and the concentration you are using would have any discernible effect on gut bacteria.

      What is most likely is that the symptoms you’re experiencing are due to oxalate release. They may feel the same as when taking antibiotics because antibiotic use an lead to oxalate buildup. So both the release and buildup of oxalates can trigger similar reactions which may be wrongly interpreted as die-off.


  25. Kay

    Paola it’s Kay again,
    Question,Im currently doing VI,RI and EI for breast/lung cancer and I do drink ozonated water. What would be the best way among what I’m currently doing for lung/breast cancer.
    I’m still learning about this but thanks for any information that you have.

    • paola d

      Hi Kay,

      I can’t give you advice how to treat your cancer.
      But I heard that some people do VI, ozone saunas and do cupping over the affected body parts while in the sauna. Whether this will help or not, I don’t know. With cancer there are often many different factors at play.


  26. Betty

    Hi Paola, thanks for the reply about the oxalate reaction. So does VI cause an oxalate release where MAH does not? I didn’t get this reaction (that feels like taking antibotics) with 4 months of intensive MAH ozone therapy (up to 5 passes). Thank you for your website!

  27. Jen

    Hi Paolo – Thank you for sharing so much and being a wonderful spirit. Do you think VI can have any positive affect on an ovarian cyst?

    • paola d

      Hi Jen,
      yes, I think it could have a positive effect.
      It’s a matter of trying it out …

  28. Kim

    Hi Paola,
    Great website! Thank you for all the information. It has been extremely helpful and I’m excited to get my own machine. I have a question about VI. I was wondering if there are any specific things I need to know since I have had a total hysterectomy.

    • paola d

      Hi Kim,
      VI can be also performed after a hysterectomy.
      This should not reduced the effectiveness of the protocol.

  29. Jacqueline

    Have you ever heard of vi healing hypothyroid. I have been doing vi almost daily for about 6 months…suddenly realized my thyroid med was making me hyper so cut it way down and feeling much better. This never happened in the 10 years that I have been taking thyroid meds only happened after many months of vi.

    • paola d

      Hi Jacqueline,
      ozone is known to increase hormone production, so this is what you may be experiencing.

  30. Nicki

    Hello, I have pudendal neuralgia which I believe is from overly tight pelvic floor muscles and it’s either trapped or irritated the nerve, so I’m in a lot of pain. Can ozone help with pelvic floor dysfunction, or pelvic floor muscle spasms etc?

    • paola d

      Hi Nicki,
      I have never heard of that particular type of condition, I had to google it.
      If there is an impinged nerve and hence inflammation, ozone could indeed help.
      I suggest a more gentle approach though first: ozone saunas.


  31. Kim Leonoudakis

    Hi, if you prefer to do VI indirectly with a bag or syringe how much would you recommend daily?

    • paola d

      Hi Kim,
      I would probably do several 200 ml syringes daily. Anything from 1 to 10 …

  32. Chris

    Hi Paola,
    Any thoughts on doing VI at the same time as a coffee enema? Any conflicts?

    • paola d

      Hi Chris,
      none that I can see …


  33. Donna

    Hi Paola,

    Would you still recommended purchasing a mask if I decided to do VI outside on my balcony?

    • paola d

      Hi Donna,



  34. Jane

    Hello Paola, i suspect parasites due to lots of small clots in menstrual fluid. Would putting ozonated olive oil reach the uterus effectively to kill them? Ozone is very new to me and i probably can’t afford a machine. Is the next easiest thing to that using syringes? Thanks for your advice 🙂

    • paola d

      Hi Jane,

      yes, you can do that. The Russians use ozonated oils for vaginal treatments. Yes, using a syringe is a good idea.


  35. Doina

    Is it ok to use ozonated oil as a lube for the VI device ( i don’t use the catheter, i use the spiral shaped VI device which is quite big and a bit difficult to insert, hence needing the lube). Or instead of the ozonated oil shall i use the water based lube?

    • paola d

      Hi Doina,

      ozonated olive oil is fine.


  36. Christie

    Is it safe in pregnancy? Want to use it to kill trichomoniasis; will it work?

    • paola d

      Hi Christie,

      it’s probably safe in pregnancy, but I would still not advise to use it for legal reasons.
      And if the tiniest complication occurs, no one will be able to tell you if it had anything to do with the ozone and you wouldn’t know either.
      If you decide to, then I would not do it after the 1st trimester.

  37. Kim Leonoudakis

    Can VI help with chronic bladder infections? If so, how often and how much for how long would possible help?

    • paola d

      Hi Kim,

      I would rather give drinking ozonated water a try.
      VI can lead to uncomfortable flare-ups.


  38. Kim Leonoudakis

    Thank you, I didn’t realize ozonated water would help. How much would you suggest drinking a day? What do you mean by uncomfortable flare-ups? I have had numerous bacterial infections in the past 14 months. Every time they do a urine test I get different bacteria showing up. I am hoping ozone could help. I didn’t think it could make it worse.

    • paola d

      Hi Kim,
      try with 1 glass on an empty stomach or at least 3 hours after your last meal.
      Increase until you reach 4 to 6 glasses.
      Wait 15 to 20 minutes after drinking it, before you eat again.

      Uncomfortable flare ups of the infection you’re dealing with. This is something that has been observed with some ozone treatments. It is explained by ozone activating a latent or chronic infection as part of the healing crisis.


    • Shannon

      Kim can you share if Ozonated Water helped your UTI? I have had them for 15 years and now have a Longevity machine and figuring out which route to take. Currently have an active UTI. Paula have you heard of people curing their UTIs with drinking the water only? Wondering if I need to do it multiple times a day or make and drink one big batch, as tolerated. Hard to always have fresh on hand.

    • paola d

      Hi Shannon,

      I have overcome UTIs with drinking ozonated water a couple of times.
      I would drink it 2 or 3 times a day when it was bad, and then tapered of to 1x a day.


  39. Raphael

    Hi Paola,

    Great post. Thank you!

    My mother had her ovary removed 31 years ago.

    Do you know if she can do vaginal insufflation with ozone?

    She suffers every year with Cystitis.

    • paola d

      Hi Raphael,

      yes, she can.
      For the cystitis I would rather try drinking ozonated water first, though.

  40. Laz

    Hello. I appreciate this site! I’ve been doing VI for almost a month now everyday for 20 minutes 1/16 Lpm… I feel a slight burn now on the left side of vaginal wall. I thought after time my body would be fully adjusted or use to the ozone. Does this mean I need to back off? I’m trying to eradicate HSV-2 and this feeling has me confused as to whether it’s an OB (even though I don’t have any itching or sores). Any insight is greatly appreciated!

    • paola d

      Hi Laz,
      what is the ozone concentration you’re getting at 1/16 LPM?

    • Laz

      In response to your question. My ozone output chart says 1/16 LPM. The ozone output says 52, which is in the high category according to the chart. I hope that is the answer to your question, as I’m still working to learn and be better in the language of ozone. Peace!

  41. Ann-Marie

    Hi Paola

    I have quite a thing going on with stage 3 uterine cancer which has spread among other areas to the cervix, which is very enlarged. The happy news first …Within 2 weeks of using ozone at a concentration of 47 ug/ml a tumour came away, it was 1 x 1.5 cm. This was most likely from the vaginal wall as cancer has spread there too, the uterus tumour is much larger at around 6 x 5 cm.

    Unfortunately, I have continued bacterial infection which is really foul, this is due to the nature of this type of cancer. The 47 ug/ml concentration was not touching the bacteria so I increased the ozone concentration to 80 ug/ml and insufflated for 2 mins rather than 20-30 mins. I have been doing this for around 5 days sometimes 2 x a day. The foul odour is halted for around 5 hours after insufflation which is a great relief.

    I have been in so much distress with these symptoms and cannot take any more antibiotics due to the effect on my gut which I am doing my best to reverse now. I am just concerned that I may cause damage to my vaginal tissue at such a high concentration of ozone. Are you able to advise me on this? I’m unsure of the effects of such a high concentration. Thank you

    • paola d

      Hi Ann-Marie,
      yes, the concentrations seems very high.
      Bring it down to 60 to 70 mcg/ml, that would be better.



  1. Five Ways to Optimize Ozone Therapy | The Power of Ozone - […] VAGINAL INSUFFLATIONS […]

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About Me

Hi! I’m Paola, the Crazy Ozone Lady and self-proclaimed ozone junkie. I've been using ozone on and off for 12 years and still discovering new things every day.

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