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The worst mistake you can make when doing ozone therapy

by | Jun 28, 2016 | 91 comments

People who commit this mistake often end up with crushing depression, they become suicidal, or have panic attacks. They report “feeling like death”, loss of hearing, debilitating tingling and burning sensations all over the body, electric shocks, or crushing back pain. Those symptoms sometimes pass after a few weeks, some last for a year or longer. Some have reported losing the ability to walk.

To make matters more confusing, this mistake often leads to an initial improvement of symptoms, just to make the same symptoms worse later on. It often leads to the emergence of new symptoms.

Given that it’s a natural compound, produced by our own cells, people have a hard time accepting how dangerous it can be. Doctors and other natural practitioners seem to be completely oblivious to the often horrific adverse reactions. When patients complain about feeling worse, it’s often explained away as a Herxheimer reaction, or as a reaction due to a genetic mutation of the patient.


The reason why you feel bad after the administration of this natural chemical has nothing to do with ozone therapy or with your genetic makeup. The reason why you have crushing headaches or “feel like dying” after the IV you received, is because your well meaning doctor has no clue about mercury toxicity.

What I’m talking about is glutathione (GSH). It’s a potent antioxidant which is often prescribed as an IV during ozone treatments.

Agreeing to glutathione IVs is one of the worst mistakes you can make when doing ozone, or any other therapy.

Medical and naturopathic doctors alike seem to have an infatuation with glutathione nowadays. It seems to be a raging fashion in the health care business. It’s given for anything from supportive cancer treatments, to general detox, liver problems, or with ozone therapy.

What most practitioners don’t know is that glutathione contains single thiols (carbon bonded sulfhydryl groups), and is therefore able to go into a weak bond with mercury.

glutathione chemical composition

Chemical composition of glutathione. The single sulfhydryl (SH) or thiol group is what makes it react with mercury.
(Picture courtesy of wikipedia, By Jjexpat.)


Why is this important?

Because mercury toxicity is probably the most widespread medical condition of our times. At the same time it’s the most misdiagnosed one.

Whatever problem you went to see your doctor for, the underlying cause may be in fact mercury toxicity. But your doctor would never know.

Mercury is in vaccines. (Yes, it’s still being LEGALLY used in vaccines in the US and most other countries.)

It’s in our tooth fillings.

It’s in our mothers’ tooth fillings who passed it on to us through the placenta before we were born.

It’s in our homes in CFL light bulbs.

Screen Shot 2016-06-28 at 7.00.21 PM

Do not expose your child or yourself to mercury from broken CFL light bulbs (pictured above). Make your home mercury free, use safe LED lights instead.

It’s in old thermometers.

It’s in the fish we eat.

It’s released from foundries, coal fired plants, and crematoriums.

… and many more places.

Our health-care systems and numerous industries rack up multi-billion dollar profits from the illnesses mercury creates.

Mercury can be the root cause of a significantly large number of health conditions listed in the medical literature including many psychiatric problems.

The brain fog, joint pain, and crushing fatigue your doctor misdiagnosed as Lyme disease? This could be the mercury you received from your flu, hepatitis, or tetanus shot.

The back pain you’ve been suffering from for years? This could be mercury from amalgam fillings you had removed 20 years ago.

The gluten intolerance, IBS (Irritable Bowel Syndrome), colitis, bleeding from your bowel? This could be from the mercury thermometer you crushed and played with as a child.

You’re unable to conceive? This could be the mercury received from your mother.

The Parksinson’s your father suffers from? Have you checked if he ever had amalgams?

Cancer, auto-immune conditions, autism, depression, anxiety, kidney disease, eczema, neurodermatitis, allergies, Multiple Sclerosis, ankylosing spondylitis, Alzheimer’s, Schizophrenia, borderline personality disorder, Attention deficit hyperactivity disorder, endocrine problems, obsessive-compulsive disorder, arthritis, lupus, multiple chemical sensitivities, chronic fatigue, fibromyalgia, sciatica, gastritis, Crohn’s disease, sleep disorders, anorexia, bulimia, candidiasis – those and more are often caused by mercury. The list is endless …

What happens when you receive glutathione intravenously?

Most mercury in our bodies is firmly bound inside our brain, liver, adrenals, digestive tract. It can be everywhere, hidden in nearly every cell of every organ, muscle, tendon. That’s why urine (including challenge tests), blood and hair tests are mostly useless for the diagnosis of mercury toxicity.

When you receive glutathione intravenously, it mobilizes mercury from deep inside these various tissues. The mercury which was firmly bound inside your liver for example, is now out in the open, floating around, mobilized by glutathione. But the glutathione does not bond to the mercury strongly enough since it has only one thiol group. Plus, your body metabolizes glutathione, so soon your GSH blood levels start to go down. The mercury will then become detached and swim around, looking to settle down again. Where will it land? Preferably, in an area where there is a lot of sulfur. That’s where mercury gets attracted to. Places like your brain, adrenals, or nerves.

So, after a course of glutathione IVs you can end up with more severe neurological symptoms like depression, inability to concentrate, inability to focus your eyes, increased brain fog, increased headaches, or body pain. Or you could  lose your ability to walk or become suicidal.

Those are typical, often reported reactions to glutathione IVs in people who have mercury.

It’s not due to your genetic makeup.

It’s not due to a healing crisis.

It has nothing to do with ozone.

It’s because your well-meaning doctor forgot to do his homework.

Glutathione does not chelate mercury. It makes mercury toxicity worse.

Similar reactions take place in mercury toxic people who ingest chlorella, cilantro, MSM, DMSO, EDTA, or high thiol foods.


How to get rid of mercury the proper way?

In order to properly remove mercury from your system, you need true chelators.

A true chelator is a chemical which satisfies the following criteria:

1) It has two thiol groups, also called a di-thiol.

2) It has a known half-life. (A half-life of a chelator is the time it takes half of the original dosage to still be detectable in the blood. Example: if you take 10mg of a chelator with a half-life of 3 hours at 12pm, then at 3pm you will have only 5mg of the chelator in your blood.)

There are currently only 3 drugs which satisfy these criteria: ALA, DMSA, and DMPS.

ALA, Alpha Lipoic Acid. It has a half life of 3 hours.

Alpha lipoic acid, chemical structure

Chemical structure of ALA, Alpha Lipoic Acid, also denominated as (R)-5-(1,2-Dithiolan-3-yl)pentanoic acid. It contains 2 thiols in a dithiolane ring (red). It is the most powerful mercury chelator since it can cross the blood brain barrier. (Picture courtesy of Wikipedia)


DMSA, Dimercaptosuccinic acid, it has a half life of 3 – 4 hours.

Chemical structure of DMSA, Dimercaptosuccinic acid. It has two thiol groups (red). (Picture courtesy of Wikipedia)

Chemical structure of DMSA, Dimercaptosuccinic acid. It has two thiol groups (red). (Picture courtesy of Wikipedia)


DMPS, Dimercaptopropanesulfonic acid, it has a half life of 6 – 8 hours.

DMPS chemical composition

Chemical structure of DMPS, Dimercaptopropanesulfonic acid, it also has 2 thiol groups (red). (Picture courtesy of wikipedia.)


Cilantro is also a di-thiol, but its half life is unknown. Hence it cannot be used safely.

In order to chelate safely and effectively one needs to take true di-thiol chelators according to their half-lives. Glutathione is a single thiol agent, hence it cannot remove mercury, only mobilize it.

Please, learn how to chelate properly by reading Andrew Cutler’s book “Amalgam Illness”, or by joining the Facebook groups “Ozone, Chelation and Paleo Diet” or “Andy Cutler Chelation Think Tank”, or read here.


Oral glutathione

There are fewer reports of adverse reactions to oral glutathione than to IV glutathione.

Why is that? Because oral glutathione is immediately broken down in the digestive tract. It’s like eating very sulfury food. People with low plasma cysteine levels (those who do better on high thiol foods) might do OK with oral glutathione. People with high plasma cysteine levels (those who do better on low thiol foods) will also do poorly on oral glutathione.

Both groups of people show high rates of adverse reactions to intravenous glutathione. Those should never be performed. But people who do better on high thiol foods usually have no or minor problems with oral glutathione.

There is a better way to raise glutathione blood levels than taking oral GSH: by taking precursors like NAC, glutamine and glycine in a 4 : 2 : 1 ratio.

People with a thiol sensitivity should not try to raise their glutathione levels.

How to know whether you’re thiol sensitive or not? Test it by excluding high thiol foods for 7 to 10 days, then introduce one high thiol food and observe your reaction. What happens when you are thiol sensitive is described on this page.


When mercury is not present, does it make sense to combine ozone with glutathione?

Some people might not have mercury toxicity to any clinically significant degree. Being completely free of mercury is impossible, since it’s part of our atmosphere and soil. But some people might have mercury levels tiny enough to not cause any pathologies. Would it then be safe to combine ozone with glutathione IVs?

No, it still would not be safe nor would it make any sense.


1) We breathe tiny amounts of mercury every day, on average 2 mcg per day. This might vary depending on how close we live to a coal fired plant, a gold mine, or an active volcano. We also consume mercury in food. So even the healthiest person will have some amount of mercury in their body. Administering such a person glutathione IVs could lead to significantly larger concentrations of mercury in the brain, causing conditions which were not present before.

2) Some studies have shown that increasing the levels of antioxidants is detrimental to one’s health. Oxidative radicals like O-, OH, H2O, and nitrogen oxides are some of the most ubiquitous molecules in our bodies. They are crucial for every single function, from digestion, to proper brain or muscle function. Taking high powered antioxidants has been linked to increased cancer metastases and to decreased athletic performance. Oxygen is life, why destroy it by taking anti-oxygen (anti-life) supplementation? This makes no sense and never has.

3) Ozone is an oxidant, glutathione is an antioxidant. Ozone pioneer Dr. Shallenberger makes a case that glutathione does not cancel out ozone to any significant degree. Yet, at the same time he says that he liked to give glutathione right before or right after a DIV (Direct ozone IV) because he would observe less vein irritation. Ozone can irritate veins when given in too high concentrations. He observed that glutathione negates ozone’s vein corroding actions. Which is in fact a perfect example of how glutathione directly counteracts ozone.

So what some people experience as glutathione minimizing Herxheimer reactions might be instead glutathione halting ozone’s necessary and therapeutic actions.

4) Ozone therapy is the best way to raise glutathione levels. The human body will naturally adjust glutathione production during ozone therapy.


Many people receive ozone IVs together with glutathione IVs. Often without full disclosure of the associated risks which are substantial. They then encounter troubling and debilitating symptoms which they attribute to a Herxheimer reaction from ozone. What is happening instead is they are experiencing a glutathione IV triggered mobilization of one of the most toxic substances on our planet, mercury.


[All mentioned adverse reactions have been taken from real life accounts posted on the “The Ozone Group” and “Andy Cutler Support Group” on Facebook.]

Recommended reading:

Amalgam Illness”, Andrew Hall Cutler, PhD.

Hair Test Interpretation: Finding Hidden Toxicities“, Andrew Hall Cutler

Mercury Poisoning: The Undiagnosed Epidemic“, David Hammond

Mercury diaries”, Daniel Forsyth

About the author:

PaolaI’m Paola the Crazy Old Ozone Lady behind The Power of Ozone. I’m a licensed naturopathic practitioner, natural health consultant, ozone therapy enthusiast, researcher, and ozone therapy analyst. I hold certificates in ozone therapy, hyperbaric ozone applications, Oxyvenierung, and the Andrew Cutler chelation. I own several ozone generators including a German hyperbaric 10 Pass machine. I have been using ozone for over 13 years, I’ve chelated with the ACC program for close to 5 years and I’ve been carnivore for nearly 1.5 years. This website serves as a resource for those who are interested in ozone therapy and other approaches to successfully manage chronic conditions. 

Legal Disclaimer

Information provided is for informational purposes only and is not a substitute for professional medical advice. No health claims for these products or treatments have been evaluated by the United States Food and Drug Administration (FDA), nor has the FDA nor any other medical authority approved these treatments or products to diagnose, cure, or prevent disease. Neither The Power of Ozone nor the manufacturers of these items are responsible for the misuse of this equipment or the information on this page. It is highly advised to receive professional council from a licensed doctor before using ozone therapy or any of the mentioned products or tests on yourself.

Affiliate Disclosure

This website contains links to vendors of products I endorse, including If you decide to make a purchase through one of my links, they will pay me a commission. This does not influence my opinion about the products, as you can see from my reviews.


  1. Beth

    I am intrigued with what I am reading on your site.
    I have gadolinium poisoning. Others like me suffer from Gadolinium poisoning too. Some have spent a fortune to try to get it removed from their bodies.
    What are your recommendations using your techniques?

    • Paola Dziwetzki

      Hi Beth,

      I don’t think there is a known way to chelate gadolinium.
      I think there may be some anecdotal evidence for glutathione helping with it, but there are also some considerable risks involved in that approach …
      I would look into treating specific symptoms directly. So, if you suffer from fatigue, see if a change in diet, certain supplements, oxygen or oxidative therapies can help you.


    • Beth

      Thank You for your response Paola.
      There is actually a Doctor in North Carolina that does chelate and he is considered the top medical authority on gadolinium poisoning. I have consulted with him but I have not treated for several reasons. I have a friend that has treated with him. What you do is similar in theory, I think, maybe. The last I heard, the Dr was going to be publishing soon too.
      So, I have actually done the things that you mentioned here. I changed my diet and have been keto for over two years. I swear swear swear by ketosis, at least for me!! So Sugar Free and gluten-free has been so good plus I eat so much healthier on the outer aisle. I have some severe neurological problems from a spinal cord and brain stem injury too. I also have significant cognitive problems from both the gadolinium poisoning and brain, brain stem, And spinal cord. My immune system started attacking me severely about 10 years ago. I had nodules in my lungs and so many other things going on. Last year my hair fell out by the handfuls and I had severe psoriasis and psoriatic arthritis and osteoarthritis.
      So I went to a rheumatologist. I am now on Humira weekly. It is my liver that is making me take more action. I began vomiting after my first MRI with gadolinium contrast in 1990. Fast forward to a few years ago, my liver functions just go through the roof and then come back down a week or two later.. Which, according to my doctors, is impossible, but there you are… If you look at my bloodwork that’s what happens, Over and over again.
      I was not aware of any risks with glutathione and gadolinium. Do you have a reference you can share with me? Coincidentally, I am taking multiple amino acids and supplements to raise my GSH. I also swear by this approach. It has helped me tremendously.
      I have also done TMS therapy and Nuro feedback/bio feedback which Helps But does not stick.

    • Anamaria

      Hi Beth,

      I am sorry to hear that. Unfortunately the same happened to me this July. Have you done anything sucessfully? Like DTPA chellation and did it work? I did my first EBO2 this week and I am feeling much better but can still feel burning sensation in my skin and trembling from Gadolinium. Have you done anything that worked for you that you can share with me too?

  2. Drew

    There are other possibilities also. I have 2 hours of well-being followed by many hours or days of severe anxiety and insomnia with oral glutathione, NAC, and whey (all taken on separate occasions). MSM does not cause problems for me. In my case, I suspect it’s a problem with glutamate or glutamic acid

    • Steven

      I was chelated with EDTA and then given glutathione by an extremely educated Environmental MD Functional Medicine doctor. I have limited circulation in my hands and feet, they are cold and tingling. I am wondering if this is a reaction as you describe. I am full of mercury which is what was keenly being chelated.

    • Paola Dziwetzki

      Hi Steven,

      how soon after the EDTA and glutathione IV did the limited circulation and cold and tingling sensations set in?

  3. Owen

    I have just found out I was given glutatheioje with my ozone

    I have been depressed since with other symptoms, what do I, please help, should I go to the hospital?

    • Paola Dziwetzki

      Hi Owen,

      I hope that the tips I gave you through messenger will help you.


  4. L.C

    Hi Paola,

    I recently received Ozone via IV therapy just two days ago. I am receiving them for a high viral load of a few different viruses and chronic fatigue syndrome. I have gotten them in the past and then stopped due to the high cost. I recently started getting them again. I had my first one a week ago.. and then my second one this past Monday. My practitioner does this by removing some of my blood.. and mixing it with ozone in a 500CC bag of NS..and thent he ozone is addded.. it then goes through a UV light machine… I am not sure of the amount or the level of ozone i received.. but after that I received an IV of glutathione push over about 10-15 mins . During the ozone IV treatment my arm started to feel crampy, and the sensation when up my arm to my shoulder. It felt tight in a sense… but the IV was certaintly in a vein.. my arm was not swollen.. but it did feel tight all the way up my shoulder.. I advised the RN but we finished the ozone therapy and moved onto the glutathione.

    After wards I felt a little woozy.. went home ate and eventually fell asleep. Yesterday and today I feel like my body is on fire, I feel very warm, but I do not have a fever. My heart feels like it is pounding, however my heart rate is around the 70s, I am a bit headachy and just feel like I have the flu in a sense. my breathing is ok.. i think its more anxiety related at this point because i am concerned about any sort of reaction or of course fatality. I read your article about glutiathione and ozone. could this be a Herx reaction? or something more serious? Im a bit concerned, I have not felt like this in the past.. and did not have this reaction last week. Do air embolisms typically occur right away? Is there anything I can do to help with the way I am feeling.. thank you for your expertise.

    • Paola Dziwetzki

      Hi L.C.,

      what you’re experiencing could be a glutathione adverse reaction.

      When you received the IVs in the past – did you get them with or without glutathione?

      What you are describing does not sound like an embolism. But more like an adverse reaction.


  5. Josh


    I am suffering from fluoroquinolone toxicity which results in 1) Chronic high levels of oxidative stress and 2) depletion of glutathione. As such typical treatment by naturopaths and functional medical docs include IV antioxidants including glutathione, NAC, and Lipoic Acid. If IVs of their antioxidants are so damaging how is one supposed to recovery from fluoroquinolone toxicity? Kind Regards, Josh

    • Paola Dziwetzki

      Hi Josh,

      I suggest to look for stories of other sufferers who have managed to overcome fluoroquinolone toxicity.

      I can give you some ideas, but I suggest to research it further.

      From what I understand, the problem is in many cases damage to connective tissue.

      Here are some ideas how to restore connective tissue health:
      – remove inflammation from your body by going on a low carb meat based ketogenic diet and by using ozone therapy
      – zinc
      – Vitamin C
      – Vitamin B 6
      – cryotherapy
      – red light therapy
      – GHK copper peptides
      – bone broths with lots of collagen
      – glutamine and glycine supplementation

      I hope this helps.


    • Josh

      Hi Paola,

      Thank you for the help. The best paper to date on FQ toxicity is titled “Treatment of the Fluoroquinolone-Associated Disability:The Pathobiochemical Implications”. It details how people experience multi-organ system damage and that the main cause is damage to the mitochondria which results in toxic levels of oxidative stress throughout the body, in part because of lower levels of glutathione. As such oral and IV intake of antioxidants including glutathione are common recommendations. You raise some good points though about the risks, so I’m trying to figure out what the best approach is. Kind Regards, Josh

    • Paola Dziwetzki

      Hi Josh,

      is the damage because of low glutathione or is the low glutathione because of the oxidative stress? Glutathione is a great marker for oxidative stress since it tends to go down when oxidation occurs. So it may be a question of chicken and egg. I haven’t read the paper though …


  6. Dan Eyink

    In our clinic we have not given Iv glutathione because of lack of clarity to what it is adding to iv vitamin c or ozone/ubi. I will say we have detoxed mercury, aluminum, lead and other metals successfully without side effects using kinesiology to help guide the choices for freeing up the metal and binding it. The levels of the metals are documented by blood, urine and symptoms. Metal flush from Chi Enterprise is one of those products that seems to work well. Your information is helpful and thought provoking. Thank you.

    • Paola Dziwetzki

      Hi Dan,
      thank you for being open minded and for considering the ideas of the Crazy Ozone Lady 😉

    • Christina

      Can you please help me?? How do I get rid of mercury with kinesiology?

    • Paola Dziwetzki

      Hi Christina,

      kinesiology is a way to diagnose conditions or deficiencies. I don’t think one can use it to chelate mercury.


  7. carly

    dear Paola, thank you for this informational post… I am currently taking ozone water which I make with a cheap machine at home it does not use oxygen… I am also using this water to wash and sit in and put a bit in the vagina too as I have large rectal tumor which has gone through vaginal wall… I have been having a glass in the morning and a glass at night on empty stomach. I have been feeling very sick and the tumor has been more painful with some burning sensation. i was also taking c60 which is what I thought was making me feel so sick so i stopped taking it but i still feeling very sick just on the ozone water… any advice would be greatly appreciated, many thanks

    • Paola Dziwetzki

      Hi carly,

      I would rather do vaginal and rectal insufflations in such a case …

      When you say “feeling very sick” after the O3 water: could you describe what exactly you’re experiencing?


  8. Shannon

    I wonder if the same is true for Liposomal Glutathione (which I have pulsed for years).

    While this makes sense, why wouldn’t the bodies own Glutathione have the same impact? A GSH IV does move the needle, but what is the estimate? 20-25%?

    Wouldn’t our normal GSH be liberating mercury at a dizzying pace at the pre-IV levels?

    Really, your thoughts do make sense….if GSH attracted a mercury bond and became subsequently metabolized, the mercury WOULD have to go somewhere. Though, I suspect the metabolism usually occurs locally (i.e. within the cell itself), and the mercury re-released locally.

    I’m actually on the fence myself with the anti-oxidant levels (Vit C, GSH, etc.) versus pro-oxidant levels (for example, DIV Ozone) and what is the most effective treatment. In my mind, reactivity isn’t 100% even when both are present in the body. In other words, there’s a probability associated with GSH finding an O3 molecule (or ozonites, O2, etc.), and it’s definitely not 100%.

    Maybe someday we’ll have more answers, but that will require funding for a substance that is dirt cheap…

  9. Martin Zelazny

    Is is ok to have nasal ozone insufflation or dental ozone shots while taking supplemental glutathione or a supplement that naturally increases glutathione?
    Also do you know why I always feel super hyper and anxious aftr taking ozonated oil capsules or suppositories?

    • Paola Dziwetzki

      Hi Martin,

      yes, it’s ok, only that you will probably not get the same benefit from ozone if you do.

      I don’t know why you feel super hyper. What type of ozonated oil is it? Olive oil? If so, maybe you have problems with salicylates?


  10. Leif

    Hi anyone had luck with ocd treatment with ozone? I’ve tried everything and gone anywhere and my OCD is so bad I literally can barely do simple tasks. I’ve thought of chelation but afraid if I don’t do it right might make my OCD worse. Last time I checked heavy metals test mercury I think was in middle range whereas tungsten was highest. But that was years ago.

    • Paola Dziwetzki

      Hi Leif,

      I used to suffer from OCD for years, what helped was exposure therapy, it’s a type of psychotherapy.


  11. david

    i am wondering if gettingiv glutathione and ozone on the same day is a bad idea (i realize you do not support iv GSH to start with)

    • Paola Dziwetzki

      Hi David,

      I think getting glutathione in general is a bad idea, so that includes doing it on the same day as ozone, yes.

      But if you space it apart from ozone by several hours, then at least this should minimize the ozone cancelling effect of the GSH.


  12. Nathan

    I made a donation how do I ask a question?.

    • Paola Dziwetzki

      Hi Nathan,

      I answered your question 2 days ago. It went to the thewhiterabbit@…. email.
      Check your inbox and your spam folder if necessary.
      Thank you for your donation!


  13. Alli

    Hello, thank you for this post. I am curious; do you feel ozone iv’s are still safe as long as a glutathione iv is not given? Thank you.

    • paola d

      Hi Alli,
      I’m afraid there is a misunderstanding.
      In this article I’m pointing out the danger of glutathione IVs, not of ozone IVs.
      As long as ozone IVs are performed by properly trained personnel with proper equipment, they’re pretty safe.
      It’s the glutathione which has a high rate of adverse reactions – which has nothing to do with ozone.


  14. Gretchen

    Hi Paola,
    My husband has WnV and EB. He recently started DIV ozone and his doc did an glut IV. After reading this I’m terrified. He feels horrid. He has a mouth full of amalgam fillings and recent had one removed.
    Obviously we will not have any more glut IVs done and will continue the Ozone therapy.
    Would you recommend removing all the fillings? Also, what chelation protocol do you recommend? There is SO much information out there it’s overwhelming. Thank you!

  15. HealtyC

    Hi Paola. Does using the ANF disc AGL or AGLS cause this same problem with interaction with ozone? From what I understand these discs help your body to naturally produce the glutathione to detox liver. I have used the disc before and it helps my migraines but have not gotten ozone yet. Thanks!

    • paola d

      Hi HealthyC,
      If you are referring to the carbonized metal discs that one applies to the body – I don’t know. I couldn’t find information what metal is involved there. If you have a link to the discs you’re using that would be helpful.

  16. Cynthia A Sands

    I just found this article and blog. Thank you so much.
    I want to say that, in trying to heal myself, I tried oral glutathione, along with some other supplements that contained thiols, and I realized very quickly that it/they were making my health problems much worse. In researching what was happening to me, I discovered the thiol connection. I can only imagine what iv glutathione would have done to me. I am currently doing ozone therapy only. I would like to know what your opinion/experience is of modified citrus pectin as a chelator. I tried it for eight months before starting the ozone therapy. Thank you so much for sharing your insight and knowledge with us.

    • paola d

      Hi Cynthia,

      thank you for posting!


  17. Mike

    Thanks Paola,

    This has been very helpful. In fact, it’s lead me to find even more information that I had no idea existed. This is why I say “stronger together”. What I didn’t know is that there is some disagreement between the experts:…/HMPTLII_Lesson24_HeavyMetalDetox.pdf

    That lead me to even more infor that Dr Sircus presents regarding the use of those natural things at home and why he things they should be used in combination:

    It’s clear to me now that it’s a continuous long-term life-time journey where we might obtain better health through an understanding of environmental toxins and a variety of detox protocols.

    There may come a time when one may have to determine which method to choose based on cost and availability, so I’ll keep this info close while I do more research to implement the best approach for me.

    Thanks again. Never stop teaching. We need more people like you.

  18. Mike

    Hi Paola,

    Over the years (about nine years) I have been researching solutions for my own health challenges associated with mercury toxicity. And, in that time I’ve run across your work on youtube and blogs helping to get good information out to people to help them heal and share your story. I always wanted to thank you for your efforts, so here’s my opportunity. Thank you. With people like yourself around we are not alone. What’s more, we are stronger together.

    After finding you again in this blog post I must ask you about the reference Dr Kondrot made in a recent blog post of his own:

    “Dr. Yoshiaki Omura, Director of Medical Research of the Heart Disease Research Foundation, Omura observed that subjects had higher than normal levels of mercury in their urine after consuming Vietnamese soup, which has large amounts of cilantro This is a good sign for if you have higher levels in your urine that means mercury is being removed from you body. He followed up on this accidental finding and discovered that giving cilantro to patients with mercury poisoning for several weeks successfully eliminated the toxin from the body. ”

    The link where this quote is found:

    This seems to be in conflict with your statement that cilantro can not be reliably used. Although he appears to support your other information in regards to chelation agents. Likewise he mentions glutathaione in playing a helpful support role in protecting against heavy metals, but not in IV therapy.

    Anyway, I would like to know what you think of Dr. Yoshiaki Omura’s research and the Dr. Kondrot’s blog post in general.

    Thanks again for all your hard work. You’ve helped a lot of people including me.

    • paola d

      Hi Mike,
      thanks for reading my blog.

      Many things can mobilize mercury and lead to an increase of mercury levels in the urine, and at the same time lead to a redistribution of mercury into sensitive tissue like brain, adrenals, liver etc. If this is done long enough, the person can be left profoundly debilitated. Doctors and patients alike rely too much on numbers on tests these days. What is relevant though are symptoms. What does it matter that urine tests showed that x mcg of mercury have been removed, if at the same time 2x mcg of mercury have accumulated in the brain, something which cannot be tested?
      The dangers of cilantro, glutathione IVs and other similar therapies are well documented with countless reports of people having been hurt by them. With chlorella and cilantro having the number 1 spot, it seems: .

      Hopt this helps.


  19. Sharon

    Hi, I have had I’v treatments with Dmso, Edta and ozone. Everything you are saying about the side effects is true. I’m feeling really Sick. I have lots of symptoms. Not sure what to do or what to take. I have been positive for Lyme I have mercury fillings etc Is there any way I can speak with you. Thanks

    • paola d

      Hi Sharon,
      so sorry to hear this happened to you!
      The best way to talk to me is by scheduling an session here
      You can also write to thepowerofozone @ but I cannot promise that I will answer in a timely fashion.
      Don’t do any more chelation IVs and please remove the mercury fillings ASAP.

    • Student of Life


      I’ve heard of these reactions u described. Ironically NAC-which is obviously a gluthione precursor-is what saved me from severe acute mercury toxicity -on top of chronic toxicity-after getting my fillings removed. V-C helped a lot after the first one, when the best high end chelators charcoal & else worked at least V-C released abt 80% of symptoms for 5-6hours per dose of buffered V-C

      I tried high dosing NAC w it the second time after hearing doctors were using it to detox mercury & it eliminated 100% of horrible mercury toxicity symptoms. I also continued to use it during the entire time I was detoxed by a toxicologist & tested negative within 6 months-which surprised me bc I’ve hear it takes an average of 3 year for most people, but pathogen loads were also plummeting & symptoms were a lot better as well.

      I’ve also nebulized synthetic gluthione when sick & felt amazing after a couple rounds.

      It’s known as the body’s master detoxifier. Why would it work so well for mercury poisoning for many people & wreck the health of others?

      The only thing I can think of is the same gene that is almost 100% correlated w autism that drastically limits the body’s ability to detox heavy metals.

      I don’t doubt these people’s stories just curious why the reaction can be the polar opposite for different people?



    • Tony

      That was so insightful. ??

    • paola d

      Thank you!

    • Ken Miller

      I have been taking IV ozone therapy for 6 weeks now but feel worse than when I first started. How can I know if my integrative Md. Is using glutathione? I ask what was in the IV and they told me it was proprietary.

    • Paola Dziwetzki

      Hi Ken,

      just ask him if the proprietary blend contains glutathione.
      If you feel worse, then I would consider stopping the treatments.
      Also, the explanation that it’s proprietary sounds like a cop-out. You’re not asking him for the exact formula, but generally what is in there.
      I would never allow anyone to inject something in me without being informed about the exact ingredients beforehand …


  21. Eduardo

    The coffee enema also generates glutathione.

    Is it a problem and one should do camomile enema instead?

    • paola d

      Hi Martin,
      it can indeed not be used with an oxygen bottle.
      Yes, it is good for ozonating water only.

      “How best is to take ozone?” – depends what you are treating or what you want to accomplish …

  22. Kay Cherry

    This blog was just sent to us by another PALS (person with ALS.) Thanks for the great information. My husband, Kim, was diagnosed over five years ago with ALS. He began using ozone in April of 2012 and has used it since then. Besides changing his diet and adding supplements and having a negative attitude toward dying of ALS, he used herbs, ozone and hyperbarics to heal. Five years ago, he could barely breathe, could not get in a body of water over his chest, had severe foot drop, losing strength in his hands, losing speech, balance, etc. He still has some foot drop and balance issues, but now his stamina has returned, he golfs, swims, walks and breathes. We feel ozone was a huge part of his healing therapies. He continues them to date.

    • paola d

      Hi Kay,
      thank you very much for sharing your husband’s story!

  23. Vickie

    Hi, thanks for the great article! I have read that when detoxing mercury it helps to take bentonite clay to help move it out of the body. Can you comment on this?

    • paola d

      Hi Vickie,
      bentonite clay will not help detox mercury out of the body as far as I know …
      For that you really need chelators taken according to their half lives.
      So ALA every 3 hours.
      DMSA every 3 to 4 hours.
      DMPS every 6 to 8 hours.

    • Alla

      Wow thank you for writing about this. I had a really bad reaction from just doing vitamin cocktail with glutathione. I literally couldn’t move. I have back pain daily but after doing this vitamin iv w glutathione I couldn’t get out of bed, back pain was much worst than I have ever experienced. I have Sjogren symptoms for few years now just sever dryness in eyes and mouth. I been wanting to try doing ozone iv therapy to remove things from my body and see if Sjogren improve with my uti’s. The doc wants to add glutathione to the iv. Now I am wondering if I should try first day w out glutathione and next day with it to see any difference. Just to compare to my last symptoms after having glutathione iv therapy.

    • Paola Dziwetzki

      Hi Alla,

      another idea may be to get just the glutathione with nothing else and see how you react to it. This will give you an idea whether your initial bad reaction had anything to do with it or with some of the other things you received.

      But for UTIs I would not concentrate on any type of IVs, but first try drinking ozonated water, or vaginal insufflations, and if that does not work, try bladder insufflations with ozone. Or soaking baths in diluted H2O2 or ozone saunas. My 2 cents …


    • Grace

      I had ozone in my mouth shots twenty my brain felt off, burning uneasy sensation. My dentist said some people will not take ozone because it makes them feel so uneasy, others will take it no issues so people will take a small amount to not go over there threshold. I had eight months of ozone IV for jaw bone infection no issues, I had it shot into my ganglion nerve center I know that crazy it was to reset my central nervous system .. I had worst, burning pain in my liver it was so bad we went to the ER. MY new doctor told me that what the hell is the ND doing, and it was wrong due to blah blah blah, but I think antibiotics have risks, even many contrast tests have risks. I think it is best to do your research and decide for yourself what will work

  24. Will

    All Robins does is ozone and he says he has done over 100000 patients, seems like he would of noticed something. Is it possible the bowel tolerance vitamin C might have a mitigating effect? It is a healing modality in and of itself, and if find many people saying C does work for detoxing mercury.

    • paola d

      Hi Will,
      millions of people have been vaccinated by thousands of doctors, one could also argue that the doctors should have noticed something, and yet most don’t, or lie to themselves that they don’t, or don’t see the damage because they don’t know what to look for.

      Yes, Vit C helps with mercury toxicity symptoms, so it could mask some of the adverse reactions.
      It does not detox mercury, though.

      An example as to doctors harming people and not realizing it: I can highly recommend joining a few self-help Facebook groups. There you will meet patients and you will find out that what the patients say is often something else from what the doctors tell you. Many, many have been harmed by doctors who continue to claim that they never saw an adverse reaction.

    • Rob

      >seems like he would of noticed something

      Nope. They pay absolutely no attention to what happens with patients, and when a patient reports an adverse reaction they deny it. I’ve experienced it myself and also seen it happen to several other people.

      Like Paoloa said it’s the same thing with vaccines, where one day the kid is fine and then after getting the vaccine the kid is a vegetable and the doctor says the kid was already like that.

      All Robins has one of the “largest track records” of at this point is damaging large numbers of unsuspecting patients. It’s not 100% certain that glutathione will damage everyone who gets it, but it’s like playing Russian roulette.

    • Robert Kern

      Most informative site I have come across. Plan on parking here. Your a beautiful and knowledgeable person. I will be donating. Thanks!!!

    • Dr Howard Robins

      This is Dr Robins
      We have performed over 245,000 Direct intravenous ozone therapies.
      We use intravenous glut with ozone in what I call a Robins Glut Sandwich.
      Half the ozone then the glut then the other half of the ozone.
      Research studies show that when ozone interacts with glut ROSs and LOPs, reactive oxygen species and lipid oxidation products are formed that continue to destroy toxins of every kind inI our bodies in addition to all virus fungus yeast mold and bacteria and eliminates harmful free radicles as well.
      We have proven through urine analysis that this method of ozone therapy can chelate mercury off nerve tissue as well as brain tissue which regular chelation therapy cannot do.
      My patients who are properly prepared by using VitC in a special way along with correct hydration do not suffer from this chelation effect.
      At least they are not complaining by phone to me as they all have my cell number have been instructed to do so or in person.
      Dr.Huggins, who was a friend, who developed the concept of the need for mercury removal and methods to do it told me over lunch one day that he did chelation therapy during the removal as 19,000 times more mercury will be released that would have if you left them during your lifetime.
      Many dentists today do not do this. Several in NYC send me their patients immediately each day after removal for RMDIV to chelate it out of blood and nerve tissue as well.
      However I do not use glut in those treatments as I want the ozone itself to work directly as much as possible and not be used up reacting with glut for chelation purposes.
      I don’t who the “many patients” are that have had negative effects that have spoken to you about ozone and glut, but they are not likely my patients.
      If you don’t understand the chemistry, I would be happy to explain it to you if you would,be kind enough to call me.

    • paola d

      Hi Dr. Robins,

      thank you for taking the time to post.
      I know you have a busy schedule.
      I really admire your work and experience with DIV, of which I am a supporter of.

      But understanding the risks of glutathione, or anything else, is first not a matter of understanding the underlying chemistry (about which I believe I do have an understanding, although I did not have lunch with Dr. Huggins, but finished a certificate course with Dr. Andrew Cutler) but first simply listening to patients. Not believing a patient and telling them “you are not going through what you are going through because you do not understand the chemistry” amounts to patient abuse in my opinion. And this is what I would be doing if I was telling people that who come to me with their horror stories. First I only listen and ask questions. This is the best one can do in order to be able to determine what happened.

      Certain people who receive glutathione IVs, without any type of ozone therapy before or after, experience horrendous side effects. This is a common observation.

      I know one person who has committed suicide because of glutathione. Before he did I had spoken with him over the phone several times and had countless chat sessions. He was going through pure hell. This was because a single glutathione IV. No ozone or anything else involved. Until his death he maintained that the glutathione IV sent him into a psychological, emotional, cognitive, and physical tailspin out of which he never recovered.

      Clearly, not everyone reacts that way.

      Many people get great benefit from glutathione.

      What is important is to know the risks involved so that adult people can make an informed decision. This is all I am trying to do.

      There are risks involved in everything, including ozone and not properly performed DIV.

      For example, there is a patient who reported that after receiving a DIV at a doctor’s office in NYC, she stumbled onto the street and collapsed and had to be taken away by ambulance. Not sure you heard about it?

      This is something that can happen if DIV is not performed properly. This is why the Oxyvenierungs Association in Germany, which trains people how to perform intravenous oxygen injections, instructs practitioners to make sure the patient remains immobile and in a horizontal or inclined position for a good 20 to 30 minutes afterwards. I can explain to you the physiological reason why this is important, if you are curious. Oxyvenierung has been done in Germany for over 60 years with growing popularity and zero fatalities.


    • Madeline

      I had simple ozone injections from Dr. Robbins about 10 years ago, and they were OK. But a personality problem developed when he made me a pair of shoe insoles that were the most uncomfortable I’ve ever had. And the most expensive. I just could not use them. Robbins kept telling me that they were good and I was somehow not perceiving that. It felt egotistical of him, bullying even. So I could imagine him denying adverse reactions from ozone patients. Anyway, I persisted in asking for my money back and he did give it to me, so good for him with that.

  25. Will

    What about Robins in NYC?
    He has done some tens of thousands and says glutathione is good to do with div, although he is strict on doing the vitamin C to bowel tollerance as well.

    He has one of the largest track records and is saying something completely contradictory to what this site is saying?

    • paola d

      All I can say is that there are many many people who report horrendous side effects after glutathione IVs.
      Many report that when they reported the adverse reactions to their doctors, they were minimized, not taken seriously, the doctor would refuse to believe them or explained it away as something else.
      I guess it is similar to the vaccine or mercury amalgam issue: thousands of doctors will swear that vaccines and amalgams are safe. And yet there are innumerable reports of the most devastating adverse reports. Children turning autistic on the same day of a vaccine. People feeling often immediate relief from symptoms like MS or arthritis after amalgam removal, yet there are thousands and thousands of dentists who will swear tooth and nail that they have never had a patient harmed by amalgam fillings.
      Doctors are also people: they see only what their mind allows them to see.

    • Christina

      Do you know of a good bio dentist to remove the teeth with the toxic fillings?

    • Paola Dziwetzki

      Hi Christina,

      there are many different good dentists. Just google one in your area.

      Make sure they use:
      – separate oxygen source for you during the removal process
      – either a rubber dam or a plastic housing to put around the single tooth with a suction tunnel attache to it
      – cutting device, not a drill, and then manual removal of the single amalgam pieces
      – extra suction
      – cold water spray to reduce mercury fumes.


  26. Susanna

    Thanks for these info are vital.
    I realized that he had some adverse reactions after taking glutathione orally
    I will never take more !!!!

    • Christina

      I’ve experienced same! I wonder if NAC Os ok?

  27. Anne Merical


    I had ispot test showing positive for lyme and coinfectiins in 8/16. I began lyme treatment using mah ozone, pemf, silver, sauna, and iv glutathione. Tx consists of 36 sessions. I am now on my 30th tx. My symptoms continue to change and worsen, with most of them being neurological in nature and debilitating. It is not herxing. Although my test results for heavy metal showed no mercury (unheard of for lyme patients), my systems match of with clinical presentation for mercury toxicity. Namely, crushing burning, tinging, and numbness that is overwhelming. And tremors, vision problems, headache, muscle spasms, and electric brain. I don’t believe these are lyme symptoms. Treating doctor disagrees and believes symptoms are from bacteria cycles of lyme such as cyst formations that continually change. My urine heavy metal test was out of range x 10 for gadolinium. Perhaps this metal is being transported around my body due to glutathione.

    • paola d

      Hi Elise,
      what other tests did you do to check for mercury poisoning, or was the urine challenge test the only one?

    • Owen

      Hi, I’m really worried here so responses would be greatly appreciated, I had ozone 10 pass on Thursday for the first time, and have been feeling unwell since, I first thought this was maybe herx, but I found this article and I’m worried it could be mercury poising!
      Basicly after the ozone, I had very sharp intense vision at times, and the day after I was super depressed and still quite depressed now. I can’t find out until tomorrow wether my dr gave me glutathione but he was administering something with a syringe while the blood was passing, should I be worried? What do I do from here

    • Grace

      It sounds to me like mold / mycotoxin poisoning you might get checked for that with a mold specialized doctor will do urine test through real time labs and then you’ll know .. Lyme and Mold illness are the great pretenders

    • bruce

      How are you after the therapy
      I dont always get to this site often so feel free to email me

    • Deborah Carter


      “My urine heavy metal test was out of range x 10 for gadolinium.”

      You have had an MRI with contrast and is more than likely the cause of your illness. Gadolinium is not found naturally in the human body. We are told by the radiologist the contrast is excreted from your body within 48 hours, but it is a lie, as you have proven with your urinalysis. Your symptoms are exactly those of Gadolinium Deposition Disease. Please see the website “GadoliniumToxicity” and you will find your answers there. There is actually a closed support group, of which I am a member, for those unknowingly poisoned by MRI contrast. There is no 100% effective chelator to remove it, but the support group provides information and hope. Take care.

  28. Kylie

    Would Max One which has the molecule RiboCeine which helps glutathione formation in the cell, be harmful too?
    ie if the body’s detoxification system is improved when it has very high levels of mercury, is a bit of a risk?

    • paola d

      I have never heard of it, sorry.
      I don’t know how it works or if at all.
      Join the Andy Cutler chelation think tank on Facebook and post that question there.

  29. Suzy Mccoppin

    AMAZING BLOG!!! do you recommend ozone without glutathione for people with mercury poisoning and parasites?

    • paola d

      Hi Suzy,
      Thank you for reading my blog.
      I would recommend ozone without glutathione for anyone doing ozone.
      For parasites, rectal insufflations could help.

    • Christina

      I had a glutathione IV push a few days ago and I thought I was going to go out of my mind!!! It was terrible. Was that likely mercury? I was wanting to do ozone roughly 5 days after the glutathione IV, is this a bad idea? Should I wait? How long should I wait past that glutathione Iv before doing ozone? Will ozone further push possible mercury in my brain? Or other unwanted places?
      I have several metal filings— (which I now want pulled and replaced with implants.)

    • Paola Dziwetzki

      Hi Christina,

      people who have mercury fillings and do glutathione IVs often report such experiences. So yes, it’s possible that what you went through was due to mercury displacement.

      I would wait until the glutathione reaction passes completely before doing anything, including ozone.

      No, ozone can not move mercury or any other metals around, but it could further overwhelm your body.

      Go on a low carb, high fat, meat based diet to give your body good proteins to be able to restore any possible damage. And wait.

      If in 2 weeks it’s not better, then let me know.


    • Grace

      Great information. Did the DMPs challenge which reveals heavy metal levels I had zero mercury in my body, but I had lead which led me to research where I grew up and found houses had lead pipes and children and adults were affected by it. I was out of the country at health resort I had two weeks straight. of chelation, followed with glutathione and nutritional IV’s Studies have shown cilantro juice is one of the strongest natural chelators. I had months of of Ozone IV , due to mystery illness, So it is good to get with an expert

  30. Daniela

    How to choose a reliable and good quality ozone generator? Trustable brands?

    • Michelle T

      Hi, I read your post on iv glutathione with ozone therapy. I have had a weird uncomfortable headache for a week now following a 10 pass with something called the pk protocol (which includes iv glutathione). Any suggestions on what I should do?

    • Paola Dziwetzki

      Hi Michelle,

      take Vitamin C, dissolve it in water and drink lots of it.

      Get a Vitamin C infusion.

      If you don’t have any amalgam fillings anymore, do a few rounds of the Andrew Cutler chelation:

      Go on the ketogenic or carnivore diet for a while. Ketosis is good for brain health.

      Feel better!


  31. Soto Martin

    Excellent analysis, there are many things to consider when evaluating therapies. No stone should be left unturned.



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