A case report.
Severe Insomnia Induced by Isotretinoin Use for the Management of Acne Vulgaris: A Rare Side Effect
https://www.cureus.com/articles/131918-severe-insomnia-induced-by-isotretinoin-use-for-the-management-of-acne-vulgaris-a-rare-side-effect
"Isotretinoin has been widely used in the management of moderate to severe acne vulgaris with great results. However, numerous side effects have been associated with its use. The association between isotretinoin and different sleep disorders has been previously established in the literature. In our literature review, we identified a relationship between isotretinoin and increased frequency of sleep apnea [1], hypersomnia [2], and improved night-time sleep [3]. To our knowledge, only one study established the relationship between isotretinoin and insomnia.
Furthermore, the use of isotretinoin for the treatment of acne has been linked to various psychiatric disorders such as depression and psychosis [4,5]. Since insomnia could be the first symptom of psychiatric disorders [4], it is essential to ask susceptible patients using isotretinoin about insomnia and other psychiatric symptoms. Here, we present a case in which a patient develops insomnia shortly after the initiation of isotretinoin for the treatment of acne."
A case report.
Severe Insomnia Induced by Isotretinoin Use for the Management of Acne Vulgaris: A Rare Side Effect
https://www.cureus.com/articles/131918-severe-insomnia-induced-by-isotretinoin-use-for-the-management-of-acne-vulgaris-a-rare-side-effect
"Isotretinoin has been widely used in the management of moderate to severe acne vulgaris with great results. However, numerous side effects have been associated with its use. The association between isotretinoin and different sleep disorders has been previously established in the literature. In our literature review, we identified a relationship between isotretinoin and increased frequency of sleep apnea [1], hypersomnia [2], and improved night-time sleep [3]. To our knowledge, only one study established the relationship between isotretinoin and insomnia.
Furthermore, the use of isotretinoin for the treatment of acne has been linked to various psychiatric disorders such as depression and psychosis [4,5]. Since insomnia could be the first symptom of psychiatric disorders [4], it is essential to ask susceptible patients using isotretinoin about insomnia and other psychiatric symptoms. Here, we present a case in which a patient develops insomnia shortly after the initiation of isotretinoin for the treatment of acne."
